{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["24(1)"],"submitter":["Sidhu V"],"pubmed_abstract":["<h4>Background</h4>This study compares the symptomatic 90-day venous thromboembolism (VTE) rates in patients receiving aspirin to patients receiving low-molecular weight heparin (LMWH) or direct oral anticoagulants (DOACs), after total hip (THA) and total knee arthroplasty (TKA).<h4>Methods</h4>Data were collected from a multi-centre cohort study, including demographics, confounders and prophylaxis type (aspirin alone, LMWH alone, aspirin and LMWH, and DOACs). The primary outcome was symptomatic 90-day VTE. Secondary outcomes were major bleeding, joint related reoperation and mortality within 90 days. Data were analysed using logistic regression, the Student's t and Fisher's exact tests (unadjusted) and multivariable regression (adjusted).<h4>Results</h4>There were 1867 eligible patients; "],"journal":["BMC musculoskeletal disorders"],"pagination":["629"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10401792"],"repository":["biostudies-literature"],"pubmed_title":["Comparative effectiveness of aspirin for symptomatic venous thromboembolism prophylaxis in patients undergoing total joint arthroplasty, a cohort study."],"pmcid":["PMC10401792"],"pubmed_authors":["Maree Naylor J","Sidhu V","Churches T","Badge H","A Harris I","Adie S"],"additional_accession":[]},"is_claimable":false,"name":"Comparative effectiveness of aspirin for symptomatic venous thromboembolism prophylaxis in patients undergoing total joint arthroplasty, a cohort study.","description":"<h4>Background</h4>This study compares the symptomatic 90-day venous thromboembolism (VTE) rates in patients receiving aspirin to patients receiving low-molecular weight heparin (LMWH) or direct oral anticoagulants (DOACs), after total hip (THA) and total knee arthroplasty (TKA).<h4>Methods</h4>Data were collected from a multi-centre cohort study, including demographics, confounders and prophylaxis type (aspirin alone, LMWH alone, aspirin and LMWH, and DOACs). The primary outcome was symptomatic 90-day VTE. Secondary outcomes were major bleeding, joint related reoperation and mortality within 90 days. Data were analysed using logistic regression, the Student's t and Fisher's exact tests (unadjusted) and multivariable regression (adjusted).<h4>Results</h4>There were 1867 eligible patients; ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-04-18T22:34:46.467Z","creation":"2025-04-07T10:19:49.889Z"},"accession":"S-EPMC10401792","cross_references":{"pubmed":["37537580"],"doi":["10.1186/s12891-023-06750-x"]}}