{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jaber M"],"funding":["Justus-Liebig-Universität Gießen","Deutsche Forschungsgemeinschaft"],"pagination":["5193-5204"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10404207"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["415(21)"],"pubmed_abstract":["The Arxula yeast bisphenol screen (A-YBS) utilizes the bioluminescent Arxula adeninivorans yeast-based reporter cells for tailored analysis of bisphenols, one of the major endocrine-disrupting compound groups. For the first time, this bioreporter has been applied on the high-performance thin-layer chromatography (HPTLC) adsorbent surface to develop a respective planar bioluminescence bioassay (pA-YBS). The goal was to combine the advantages of HPTLC with a more selective bioassay detection for bisphenols. The performance of this pA-YBS bioluminescence bioassay was demonstrated by calculating the half-maximal effective concentration (EC<sub>50</sub>) of bisphenols compared to references. The EC<sub>50</sub> ranged from 267 pg/band for bisphenol Z and 322 pg/band for bisphenol A (BPA) to > 1"],"journal":["Analytical and bioanalytical chemistry"],"pubmed_title":["Screening bisphenols in complex samples via a planar Arxula adeninivorans bioluminescence bioassay."],"pmcid":["PMC10404207"],"funding_grant_id":["INST 162/536-1 FUGG","INST 162/471-1 FUGG"],"pubmed_authors":["Jaber M","Oberle M","Jahne M","Morlock GE"],"additional_accession":[]},"is_claimable":false,"name":"Screening bisphenols in complex samples via a planar Arxula adeninivorans bioluminescence bioassay.","description":"The Arxula yeast bisphenol screen (A-YBS) utilizes the bioluminescent Arxula adeninivorans yeast-based reporter cells for tailored analysis of bisphenols, one of the major endocrine-disrupting compound groups. For the first time, this bioreporter has been applied on the high-performance thin-layer chromatography (HPTLC) adsorbent surface to develop a respective planar bioluminescence bioassay (pA-YBS). The goal was to combine the advantages of HPTLC with a more selective bioassay detection for bisphenols. The performance of this pA-YBS bioluminescence bioassay was demonstrated by calculating the half-maximal effective concentration (EC<sub>50</sub>) of bisphenols compared to references. The EC<sub>50</sub> ranged from 267 pg/band for bisphenol Z and 322 pg/band for bisphenol A (BPA) to > 1","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2026-06-05T07:04:50.373Z","creation":"2025-04-07T04:30:59.292Z"},"accession":"S-EPMC10404207","cross_references":{"pubmed":["37458782"],"doi":["10.1007/s00216-023-04820-6"]}}