{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tamari R"],"funding":["NCI NIH HHS"],"pagination":["3993-4002"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10410129"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(15)"],"pubmed_abstract":["To develop a prognostic model for patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) for myelofibrosis (MF), we examined the data of 623 patients undergoing allo-HCT between 2000 and 2016 in the United States (the Center for International Blood and Marrow Transplant Research [CIBMTR] cohort). A Cox multivariable model was used to identify factors prognostic of mortality. A weighted score using these factors was assigned to patients who received transplantation in Europe (the European Bone Marrow Transplant [EBMT] cohort; n = 623). Patient age >50 years (hazard ratio [HR], 1.39; 95% confidence interval [CI], 0.98-1.96), and HLA-matched unrelated donor (HR, 1.29; 95% CI, 0.98-1.7) were associated with an increased hazard of death and were assigned 1 point. Hemoglobi"],"journal":["Blood advances"],"pubmed_title":["A simple prognostic system in patients with myelofibrosis undergoing allogeneic stem cell transplantation: a CIBMTR/EBMT analysis."],"pmcid":["PMC10410129"],"funding_grant_id":["U24 CA076518"],"pubmed_authors":["Ganguly S","Agrawal V","Yared JA","Pu JJ","Grunwald MR","Gale RP","Battiwalla M","Beitinjaneh A","Nathan S","Estrada-Merly N","Giralt S","Tamari R","Cutler C","Marks DI","Bredeson C","DeFilipp Z","Diaz MA","Bashey A","Verdonck LF","Gergis U","Abid MB","Nakamura R","Savani BN","Jain T","McLornan DP","Hashmi S","Scott BL","Kharfan-Dabaja MA","Oran B","Czerw T","Nishihori T","Yakoub-Agha I","Litzow MR","Liesveld J","Ulrike Bacher V","Rizzieri D","Ali H","Aljurf M","Hildebrandt GC","Gupta V","Lazarus HM","van der Poel M","Pawarode A","Saber W","Hernandez-Boluda JC","Seo S","Ahn KW","Solh MM","Kindwall-Keller T","Palmer J","Wirk B"],"additional_accession":[]},"is_claimable":false,"name":"A simple prognostic system in patients with myelofibrosis undergoing allogeneic stem cell transplantation: a CIBMTR/EBMT analysis.","description":"To develop a prognostic model for patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) for myelofibrosis (MF), we examined the data of 623 patients undergoing allo-HCT between 2000 and 2016 in the United States (the Center for International Blood and Marrow Transplant Research [CIBMTR] cohort). A Cox multivariable model was used to identify factors prognostic of mortality. A weighted score using these factors was assigned to patients who received transplantation in Europe (the European Bone Marrow Transplant [EBMT] cohort; n = 623). Patient age >50 years (hazard ratio [HR], 1.39; 95% confidence interval [CI], 0.98-1.96), and HLA-matched unrelated donor (HR, 1.29; 95% CI, 0.98-1.7) were associated with an increased hazard of death and were assigned 1 point. Hemoglobi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-04-05T00:22:58.734Z","creation":"2025-04-05T00:22:58.734Z"},"accession":"S-EPMC10410129","cross_references":{"pubmed":["37134306"],"doi":["10.1182/bloodadvances.2023009886"]}}