{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Young LW"],"funding":["Eunice Kennedy Shriver National Institute of Child Health and Human Development","NICHD NIH HHS","NCATS NIH HHS","National Institutes of Health","NIH HHS"],"pagination":["2326-2337"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10433732"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["388(25)"],"pubmed_abstract":["Background
Although clinicians have traditionally used the Finnegan Neonatal Abstinence Scoring Tool to assess the severity of neonatal opioid withdrawal, a newer function-based approach - the Eat, Sleep, Console care approach - is increasing in use. Whether the new approach can safely reduce the time until infants are medically ready for discharge when it is applied broadly across diverse sites is unknown.Methods
In this cluster-randomized, controlled trial at 26 U.S. hospitals, we enrolled infants with neonatal opioid withdrawal syndrome who had been born at 36 weeks' gestation or more. At a randomly assigned time, hospitals transitioned from usual care that used the Finnegan tool to the Eat, Sleep, Console approach. During a 3-month transition period, staff members at ea"],"journal":["The New England journal of medicine"],"pubmed_title":["Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal."],"pmcid":["PMC10433732"],"funding_grant_id":["UG1 HD068278","U24OD024957","1U24HD095254","UG1 OD024958","UG1 OD024959","UG1 OD024943","UG1 OD024945","3U2COD023375","UG1 OD024942","UG1 HD027853","U2C OD023375","UG1 HD087226","UG1 HD040492","U10 HD036790","U24 OD024957","UG1 HD068244","UG1 HD068263","UG1 HD053109","U01 HD036790","UL1 TR001117","U24 HD095254","UG1 OD024947","UG1 OD024948","UG1 HD053089","UG1 OD024954","UG1 OD024955","UG1 OD024956","UG1 OD024950","UG1 OD024953","UG1 HD021364"],"pubmed_authors":["Akshatha","Maxwell JR","Crawford MM","Crowley M","Hu Z","Higgins RD","Hahn DW","Smith PB","Howell MP","PhD AD","Wright T","Ounpraseuth S","Ounpraseuth ST","Merhar SL","Simon AE","Reynolds AM","McAllister JM","Greenberg RG","Rice W","Braswell EF","McAlmon KR","Bremer AA","Ross J","Shaikh SK","Snowden JN","Newman S","Akshatha A","Riccio J","Dummula K","ACT NOW Collaborative","Weiner J","Lee JY","Walsh MC","Wong Ramsey K","Paul DA","Devlin LA","Young LW","Puopolo KM","White JR","Christ L","Brown J","Ms ZH","Poindexter BB","Fung CM","Das A","Tucker L","Telang S"],"additional_accession":[]},"is_claimable":false,"name":"Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal.","description":"Background
Although clinicians have traditionally used the Finnegan Neonatal Abstinence Scoring Tool to assess the severity of neonatal opioid withdrawal, a newer function-based approach - the Eat, Sleep, Console care approach - is increasing in use. Whether the new approach can safely reduce the time until infants are medically ready for discharge when it is applied broadly across diverse sites is unknown.Methods
In this cluster-randomized, controlled trial at 26 U.S. hospitals, we enrolled infants with neonatal opioid withdrawal syndrome who had been born at 36 weeks' gestation or more. At a randomly assigned time, hospitals transitioned from usual care that used the Finnegan tool to the Eat, Sleep, Console approach. During a 3-month transition period, staff members at ea","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2026-05-28T13:02:27.355Z","creation":"2025-04-06T16:28:33.892Z"},"accession":"S-EPMC10433732","cross_references":{"pubmed":["37125831"],"doi":["10.1056/NEJMoa2214470","10.1056/nejmoa2214470"]}}