biostudies-literatureUnknown53(8)Hong JA<h4>Background and objectives</h4>Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to eventual heart transplantation (HT) is increasingly used worldwide. However, the effect of different VA-ECMO types on HT outcomes remains unclear.<h4>Methods</h4>This was a retrospective observational study of 111 patients receiving VA-ECMO and awaiting HT. We assessed 3 ECMO configuration groups: peripheral (n=76), central (n=12), and peripheral to central ECMO conversion (n=23). Cox proportional hazards regression and landmark analysis were conducted to analyze the effect of the ECMO configuration on HT and in-hospital mortality rates. We also evaluated adverse events during ECMO support.<h4>Results</h4>HT was performed in the peripheral (n=48, 63.2%), central (n=10, 83.3%), and cKorean circulation journal535-547https://www.ebi.ac.uk/biostudies/studies/S-EPMC10435828biostudies-literatureComparison of Veno-arterial Extracorporeal Membrane Oxygenation Configurations for Patients Listed for Heart Transplantation.PMC10435828Jung SHKim MSPack DKim JJKim ARHyun JLee SEKim MJKang PJHong JAfalseComparison of Veno-arterial Extracorporeal Membrane Oxygenation Configurations for Patients Listed for Heart Transplantation.<h4>Background and objectives</h4>Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to eventual heart transplantation (HT) is increasingly used worldwide. However, the effect of different VA-ECMO types on HT outcomes remains unclear.<h4>Methods</h4>This was a retrospective observational study of 111 patients receiving VA-ECMO and awaiting HT. We assessed 3 ECMO configuration groups: peripheral (n=76), central (n=12), and peripheral to central ECMO conversion (n=23). Cox proportional hazards regression and landmark analysis were conducted to analyze the effect of the ECMO configuration on HT and in-hospital mortality rates. We also evaluated adverse events during ECMO support.<h4>Results</h4>HT was performed in the peripheral (n=48, 63.2%), central (n=10, 83.3%), and c2023-01-01T00:00:00Z2023 Aug2025-04-05T11:11:31.204Z2025-04-05T11:11:31.204ZS-EPMC104358283727175210.4070/kcj.2022.0348