biostudies-literatureUnknown11(16)Ruffolo AF<h4>Objective</h4>To evaluate the impact of systemic sclerosis (SSc) on vulvovaginal atrophy (VVA) and sexual health in an Italian population.<h4>Methods</h4>An Italian survey about the prevalence and severity of VVA (on a 0 to 10 scale) and sexual dysfunction (using the Female Sexual Function Index-FSFI) through an anonymous online questionnaire. We investigated couple relationships and intimacy with partners, the predisposition of patients to talk about their sexual problems, physicians' receptivity, and treatment scenarios. Risk factors for VVA symptoms and sexual dysfunction were assessed.<h4>Results</h4>A total of 107 women affected by SSc were enrolled. Of these, 83.2% of women (89/107) complained about VVA symptoms and 89.7% (among sexually active women; 87/97) about sexual dysfunctHealthcare (Basel, Switzerland)2346https://www.ebi.ac.uk/biostudies/studies/S-EPMC10454073biostudies-literatureThe Impact of Systemic Sclerosis on Sexual Health: An Italian Survey.PMC10454073Garbagnati CScancarello CDi Dedda MCCasiraghi ABraga ARuffolo AFSalvatore SCandiani MBenini VSerati MfalseThe Impact of Systemic Sclerosis on Sexual Health: An Italian Survey.<h4>Objective</h4>To evaluate the impact of systemic sclerosis (SSc) on vulvovaginal atrophy (VVA) and sexual health in an Italian population.<h4>Methods</h4>An Italian survey about the prevalence and severity of VVA (on a 0 to 10 scale) and sexual dysfunction (using the Female Sexual Function Index-FSFI) through an anonymous online questionnaire. We investigated couple relationships and intimacy with partners, the predisposition of patients to talk about their sexual problems, physicians' receptivity, and treatment scenarios. Risk factors for VVA symptoms and sexual dysfunction were assessed.<h4>Results</h4>A total of 107 women affected by SSc were enrolled. Of these, 83.2% of women (89/107) complained about VVA symptoms and 89.7% (among sexually active women; 87/97) about sexual dysfunct2023-01-01T00:00:00Z2023 Aug2025-04-26T23:41:10.543Z2025-04-06T17:35:14.592ZS-EPMC104540733762854310.3390/healthcare11162346