biostudies-literatureSerrano-Garcia IMinistry of Science and Innovation (Spain)Special Research Programme of the University of GrandaMillennium Science Initiative Program3004https://www.ebi.ac.uk/biostudies/studies/S-EPMC10458757biostudies-literatureUnknown12(16)Spain dominates avocado production in Europe, with the <i>Hass</i> variety being the most prominent. Despite this, Spanish production satisfies less than 10% of the overall avocado demand in Europe. Consequently, the European avocado market heavily relies on imports from overseas, primarily sourced from Peru and Chile. Herein, a comprehensive characterization of the metabolic profile of <i>Hass</i> avocado fruits from Spain, Peru, and Chile, available in the European market throughout the year, was carried out. The determination of relevant substances was performed using high- and low-resolution RP-LC-MS. Remarkable quantitative differences regarding phenolic compounds, amino acids, and nucleosides were observed. Principal component analysis revealed a natural clustering of avocados accordPlants (Basel, Switzerland)Assessing the RP-LC-MS-Based Metabolic Profile of <i>Hass</i> Avocados Marketed in Europe from Different Geographical Origins (Peru, Chile, and Spain) over the Whole Season.PMC10458757PID2021-128508OB-I00PID2019-109566RB-I00PPJIA2022.39ICN2021_044Serrano-Garcia IOlmo-Garcia LHurtado-Fernandez EGonzalez-Fernandez JJHormaza JIDominguez-Garcia JCarrasco-Pancorbo ABeiro-Valenzuela MGMonasterio RPedreschi RfalseAssessing the RP-LC-MS-Based Metabolic Profile of <i>Hass</i> Avocados Marketed in Europe from Different Geographical Origins (Peru, Chile, and Spain) over the Whole Season.Spain dominates avocado production in Europe, with the <i>Hass</i> variety being the most prominent. Despite this, Spanish production satisfies less than 10% of the overall avocado demand in Europe. Consequently, the European avocado market heavily relies on imports from overseas, primarily sourced from Peru and Chile. Herein, a comprehensive characterization of the metabolic profile of <i>Hass</i> avocado fruits from Spain, Peru, and Chile, available in the European market throughout the year, was carried out. The determination of relevant substances was performed using high- and low-resolution RP-LC-MS. Remarkable quantitative differences regarding phenolic compounds, amino acids, and nucleosides were observed. Principal component analysis revealed a natural clustering of avocados accord2023-01-01T00:00:00Z2023 Aug2025-06-01T00:59:52.821Z2025-06-01T00:59:52.821ZS-EPMC104587573763121510.3390/plants12163004