biostudies-literatureUnknown6(8)Revol B<h4>Importance</h4>The DRAMES (Décès en Relation avec l'Abus de Médicaments Et de Substances) register is a database of drug-related deaths with the aim of identifying the psychoactive substances associated with and estimating the trends in these deaths. Our novel approach is based on the collection of data on all deaths for which toxicology experts have performed analyses.<h4>Objective</h4>To describe drug-related deaths in France and report trends over an 11-year period.<h4>Design, setting, and participants</h4>This case series used a national register to assess 4460 drug-related deaths that occurred from 2011 to 2021 in France. Data analyses were performed from January 1, 2012, to December 31, 2022.<h4>Main outcomes and measures</h4>Demographic characteristics; medical and substance abuJAMA network opene2331398https://www.ebi.ac.uk/biostudies/studies/S-EPMC10469283biostudies-literatureTrends in Fatal Poisoning Among Drug Users in France From 2011 to 2021: An Analysis of the DRAMES Register.PMC10469283Kintz PSpadari MLamiable DRevol BMathieu OVenisse NBouquet EDelage MLavit MKergueris MFDelavenne XGaillard YMorel IPepin GBarret ACitterio-Quentin AAquizerate AFouley AVisinoni PLopez VEiden CSibille PGoulle JPGaniere CDevos BHoizey GGambier NLelievre BChaouachi LTitier KGaulier JMLefeuvre SCompagnie Nationale des Biologistes et Analystes Experts (CNBAE) and the French Addictovigilance Network (FAN)Mura PBillet-Chatenay CFouilhe Sam-Lai NDeffontaine GLelong-Boulouard VBourgine JDaveluy ALe Meur CPelissier-Alicot ALLabat-Deveaux LKlinzig FBertin CMathieu-Daude JCPerrin MRoman ERoussin AWilleman TSabini SCheze MLoilier MBesnard TGuerard PBerland ELima-Tournebize JTurcant ADeslandes GRoussel CDailly EMauras YDescoeur JLemaire-Hurtel ASAmeline APeyre ARayer RVacher PSaussereau EVieira OHumbert LLacroix CMartin-Molins CAbbara CPok RAllorge DMilan NImbert LDoche CChevallier CAlvarez JCCaous ASPineau ACesbron AMoal ABrunet BLacarelle BEysseric-Guerin HMarty HDescamps FDeveaux MDumestre-Toulet VBevalot FScala-Bertola JRagoucy-Sengler CLe Boisselier RManceau MCollon-Fabie PLe Bouil AfalseTrends in Fatal Poisoning Among Drug Users in France From 2011 to 2021: An Analysis of the DRAMES Register.<h4>Importance</h4>The DRAMES (Décès en Relation avec l'Abus de Médicaments Et de Substances) register is a database of drug-related deaths with the aim of identifying the psychoactive substances associated with and estimating the trends in these deaths. Our novel approach is based on the collection of data on all deaths for which toxicology experts have performed analyses.<h4>Objective</h4>To describe drug-related deaths in France and report trends over an 11-year period.<h4>Design, setting, and participants</h4>This case series used a national register to assess 4460 drug-related deaths that occurred from 2011 to 2021 in France. Data analyses were performed from January 1, 2012, to December 31, 2022.<h4>Main outcomes and measures</h4>Demographic characteristics; medical and substance abu2023-01-01T00:00:00Z2023 Aug2025-04-04T22:55:26.4Z2024-12-03T17:55:05.056ZS-EPMC104692833764706610.1001/jamanetworkopen.2023.31398