biostudies-literatureMagarakis LUmeå UniversitySwedish state under the agreement between the Swedish government and the county councils, the ALF-agreementSwedish Cancer SocietyCenter for clinical research county of VärmlandLena Wäppling foundatione071246https://www.ebi.ac.uk/biostudies/studies/S-EPMC10481827biostudies-literatureUnknown13(9)<h4>Introduction</h4>Salpingectomy is currently suggested as an alternative to tubal ligation for sterilisation. Precursor lesions of ovarian carcinoma can be found in the fallopian tubes; thus, salpingectomy could possibly reduce the incidence. Most of the existing trials on safety are small, on caesarean section and report on surrogate ovarian function measures. Randomised trials in laparoscopy are lacking. Well-designed trials are needed to evaluate safety of laparoscopic opportunistic salpingectomy.<h4>Methods and analysis</h4>In SALSTER, a national register-based randomised controlled non-inferiority trial, 968 women <50 years, wishing laparoscopic sterilisation will be randomised to either salpingectomy or tubal ligation. The Swedish National Quality Register of Gynecological SurgeryBMJ openSALpingectomy for STERilisation (SALSTER): study protocol for a Swedish multicentre register-based randomised controlled trial.PMC10481827LIVFOU-929703ALFGBG-965130 and ALF RegVB-969584N/A for the award/grant number21 1408 PjIdahl ALiv PSundfeldt KPalsson MStrandell AMagarakis LfalseSALpingectomy for STERilisation (SALSTER): study protocol for a Swedish multicentre register-based randomised controlled trial.<h4>Introduction</h4>Salpingectomy is currently suggested as an alternative to tubal ligation for sterilisation. Precursor lesions of ovarian carcinoma can be found in the fallopian tubes; thus, salpingectomy could possibly reduce the incidence. Most of the existing trials on safety are small, on caesarean section and report on surrogate ovarian function measures. Randomised trials in laparoscopy are lacking. Well-designed trials are needed to evaluate safety of laparoscopic opportunistic salpingectomy.<h4>Methods and analysis</h4>In SALSTER, a national register-based randomised controlled non-inferiority trial, 968 women <50 years, wishing laparoscopic sterilisation will be randomised to either salpingectomy or tubal ligation. The Swedish National Quality Register of Gynecological Surgery2023-01-01T00:00:00Z2023 Sep2026-05-29T03:52:22.897Z2024-11-06T07:00:12.304ZS-EPMC104818273766654810.1136/bmjopen-2022-071246