{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Hansel M"],"pubmed_abstract":["<h4>Objective</h4>Patients' olfactory function after autoimmune encephalitis (AE) involving limbic structures may be impaired. This study aimed to characterize olfactory function in patients after autoimmune encephalitides.<h4>Methods</h4>A case-control study was performed including 11 AE patients with antibodies against NMDAR (<i>n</i> = 4), GAD (<i>n</i> = 3), VGKC (<i>n</i> = 3) and antibody-negative AE (<i>n</i> = 1) and a control group of 12 patients with pneumococcal meningo-encephalitis (PC). In subgroup analyses, AE patients with and without NMDAR-antibodies were compared. Olfactory function was assessed using the Sniffin Sticks test and the resulting TDI-score (threshold, discrimination, identification). Involvement of limbic structures was evaluated on imaging data (MRI). Statist"],"journal":["Frontiers in neurology"],"pagination":["1225975"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10486887"],"repository":["biostudies-literature"],"pubmed_title":["Olfactory dysfunction after autoimmune encephalitis depending on the antibody type and limbic MRI pathologies."],"pmcid":["PMC10486887"],"pubmed_authors":["Schneider H","Reichmann H","Schmitz-Peiffer H","Hansel M","Hahner A"],"additional_accession":[]},"is_claimable":false,"name":"Olfactory dysfunction after autoimmune encephalitis depending on the antibody type and limbic MRI pathologies.","description":"<h4>Objective</h4>Patients' olfactory function after autoimmune encephalitis (AE) involving limbic structures may be impaired. This study aimed to characterize olfactory function in patients after autoimmune encephalitides.<h4>Methods</h4>A case-control study was performed including 11 AE patients with antibodies against NMDAR (<i>n</i> = 4), GAD (<i>n</i> = 3), VGKC (<i>n</i> = 3) and antibody-negative AE (<i>n</i> = 1) and a control group of 12 patients with pneumococcal meningo-encephalitis (PC). In subgroup analyses, AE patients with and without NMDAR-antibodies were compared. Olfactory function was assessed using the Sniffin Sticks test and the resulting TDI-score (threshold, discrimination, identification). Involvement of limbic structures was evaluated on imaging data (MRI). Statist","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-04T19:37:29.738Z","creation":"2025-04-04T19:37:29.738Z"},"accession":"S-EPMC10486887","cross_references":{"pubmed":["37693764"],"doi":["10.3389/fneur.2023.1225975"]}}