{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tiranakwit T"],"funding":["The Research Fund for Supporting Lecturers to Admit High Potential Students to Study and Re-search in her Expert Program Year 2021, Khon Kaen University."],"pagination":["13425"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10487580"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(17)"],"pubmed_abstract":["The antioxidant activity of a traditional Thai formula has been studied and compared to each plant. The formula comprised the roots of <i>Caesalpinia digyna</i> Rottler, <i>Huberantha cerasoides</i> (Roxb.) Benth), <i>Oxyceros horridus</i> Lour, <i>Antidesma ghaesembilla</i> Gaerth, <i>Combretum quadrangulare</i> Kurz, and <i>Ziziphus cambodiana</i> Pierre. The stem was also studied in comparison. The ethanolic extract from each plant part and the mixed plants mimicking the traditional formula were prepared and investigated for antioxidant capability in vitro via DPPH radical scavenging and ferric-reducing antioxidant power assays. The phytochemical constituents were determined by chemical screening, total phenolic (TPC) and flavonoid contents (TFC), and high-performance liquid chromatography. The relationship between antioxidant activity and the contributed phytochemicals was determined using correlation analysis and principal component analysis (PCA). Results showed that extracts from both parts of the plant formula showed the highest antioxidant activity compared to a single plant extract. Among the six plants, <i>C. digyna</i> exhibited the highest TPC and antioxidant activity. TPC had a strong positive correlation with antioxidant activity. PCA revealed that gallic acid contributed to the antioxidant activity. In conclusion, the ethanolic extracts of the traditional formula and <i>C. digyna</i> have the potential for further chemical characterization and study related to antioxidant activity."],"journal":["International journal of molecular sciences"],"pubmed_title":["Phytochemical Screening on Phenolic, Flavonoid Contents, and Antioxidant Activities of Six Indigenous Plants Used in Traditional Thai Medicine."],"pmcid":["PMC10487580"],"funding_grant_id":["641H112"],"pubmed_authors":["Puangpun W","Wichai N","Weerapreeyakul N","Tamprasit K","Srisongkram T","Tiranakwit T","Siriamornpun S"],"additional_accession":[]},"is_claimable":false,"name":"Phytochemical Screening on Phenolic, Flavonoid Contents, and Antioxidant Activities of Six Indigenous Plants Used in Traditional Thai Medicine.","description":"The antioxidant activity of a traditional Thai formula has been studied and compared to each plant. The formula comprised the roots of <i>Caesalpinia digyna</i> Rottler, <i>Huberantha cerasoides</i> (Roxb.) Benth), <i>Oxyceros horridus</i> Lour, <i>Antidesma ghaesembilla</i> Gaerth, <i>Combretum quadrangulare</i> Kurz, and <i>Ziziphus cambodiana</i> Pierre. The stem was also studied in comparison. The ethanolic extract from each plant part and the mixed plants mimicking the traditional formula were prepared and investigated for antioxidant capability in vitro via DPPH radical scavenging and ferric-reducing antioxidant power assays. The phytochemical constituents were determined by chemical screening, total phenolic (TPC) and flavonoid contents (TFC), and high-performance liquid chromatography. The relationship between antioxidant activity and the contributed phytochemicals was determined using correlation analysis and principal component analysis (PCA). Results showed that extracts from both parts of the plant formula showed the highest antioxidant activity compared to a single plant extract. Among the six plants, <i>C. digyna</i> exhibited the highest TPC and antioxidant activity. TPC had a strong positive correlation with antioxidant activity. PCA revealed that gallic acid contributed to the antioxidant activity. In conclusion, the ethanolic extracts of the traditional formula and <i>C. digyna</i> have the potential for further chemical characterization and study related to antioxidant activity.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-05-29T19:50:27.326Z","creation":"2025-04-05T20:56:10.889Z"},"accession":"S-EPMC10487580","cross_references":{"pubmed":["37686230"],"doi":["10.3390/ijms241713425"]}}