biostudies-literatureHe JMajor Project of Talent Support Plan of Anhui University of Chinese MedicineOutstanding Youth Scientific Research Project of Department of Education of Anhui ProvinceNational Natural Science Foundation of ChinaNational Key Research and Development Program of China13174https://www.ebi.ac.uk/biostudies/studies/S-EPMC10488261biostudies-literatureUnknown24(17)In this study, bipolar membrane electrodialysis was proposed to directly convert L-ornithine monohydrochloride to L-ornithine. The stack configuration was optimized in the BP-A (BP, bipolar membrane; A, anion exchange membrane) configuration with the Cl^- ion migration through the anion exchange membrane rather than the BP-A-C (C, cation exchange membrane) and the BP-C configurations with the L-ornithine⁺ ion migration through the cation exchange membrane. Both the conversion ratio and current efficiency follow BP-A > BP-A-C > BP-C, and the energy consumption follows BP-A < BP-A-C < BP-C. Additionally, the voltage drop across the membrane stack (two repeating units) and the feed concentration were optimized as 7.5 V and 0.50 mol/L, respectively, due to the low value ofInternational journal of molecular sciencesBipolar Membrane Electrodialysis for Direct Conversion of L-Ornithine Monohydrochloride to L-Ornithine.PMC104882612022AH0300632022YFB3805103220082262022rcZD005Fang YTian ZSun LZheng ZHao JLi CHe JLiang YMa XYan HLiu WfalseBipolar Membrane Electrodialysis for Direct Conversion of L-Ornithine Monohydrochloride to L-Ornithine.In this study, bipolar membrane electrodialysis was proposed to directly convert L-ornithine monohydrochloride to L-ornithine. The stack configuration was optimized in the BP-A (BP, bipolar membrane; A, anion exchange membrane) configuration with the Cl^- ion migration through the anion exchange membrane rather than the BP-A-C (C, cation exchange membrane) and the BP-C configurations with the L-ornithine⁺ ion migration through the cation exchange membrane. Both the conversion ratio and current efficiency follow BP-A > BP-A-C > BP-C, and the energy consumption follows BP-A < BP-A-C < BP-C. Additionally, the voltage drop across the membrane stack (two repeating units) and the feed concentration were optimized as 7.5 V and 0.50 mol/L, respectively, due to the low value of2023-01-01T00:00:00Z2023 Aug2025-05-29T19:51:03.875Z2025-04-05T20:56:59.02ZS-EPMC104882613768598210.3390/ijms241713174