biostudies-literatureUnknown12(17)Dibos M<h4>Background</h4>In past influenza pandemics and the current COVID-19 pandemic, bacterial endotracheal superinfections are a well-known risk factor for higher morbidity and mortality. The goal of this study was to investigate the influence of a structured, objective, microbiological monitoring program on the prognosis of COVID-19 patients with mechanical ventilation.<h4>Methods</h4>A structured microbiological monitoring program (at intubation, then every 3 days) included collection of endotracheal material. Data analysis focused on the spectrum of bacterial pathogens, mortality, as well as intensive care unit (ICU), hospital, and mechanical ventilation duration.<h4>Results</h4>A total of 29% of the patients showed bacterial coinfection at the time of intubation, and within 48 h, 56% devJournal of clinical medicine5622https://www.ebi.ac.uk/biostudies/studies/S-EPMC10488947biostudies-literatureInfluence of a Structured Microbiological Endotracheal Monitoring Program on the Outcome of Critically Ill COVID-19 Patients: An Observational Study.PMC10488947Dibos MRasch SLahmer TSchmid RMHaschka SJAbbassi RSchneider JfalseInfluence of a Structured Microbiological Endotracheal Monitoring Program on the Outcome of Critically Ill COVID-19 Patients: An Observational Study.<h4>Background</h4>In past influenza pandemics and the current COVID-19 pandemic, bacterial endotracheal superinfections are a well-known risk factor for higher morbidity and mortality. The goal of this study was to investigate the influence of a structured, objective, microbiological monitoring program on the prognosis of COVID-19 patients with mechanical ventilation.<h4>Methods</h4>A structured microbiological monitoring program (at intubation, then every 3 days) included collection of endotracheal material. Data analysis focused on the spectrum of bacterial pathogens, mortality, as well as intensive care unit (ICU), hospital, and mechanical ventilation duration.<h4>Results</h4>A total of 29% of the patients showed bacterial coinfection at the time of intubation, and within 48 h, 56% dev2023-01-01T00:00:00Z2023 Aug2025-05-29T19:51:52.875Z2025-04-05T20:55:00.681ZS-EPMC104889473768568910.3390/jcm12175622