biostudies-literatureDiaz JNational Agency For Research and Development - Chile6368https://www.ebi.ac.uk/biostudies/studies/S-EPMC10490183biostudies-literatureUnknown28(17)The catalytic oxidation of phenethoxybenzene as a lignin model compound with a β-O-4 bond was conducted using the Keggin-type polyoxometalate nanocatalyst (TBA)₅[PMo₁₀V₂O₄₀]. The optimization of the process's operational conditions was carried out using response surface methodology. The statistically significant variables in the process were determined using a fractional factorial design. Based on this selection, a central circumscribed composite experimental design was used to maximize the phenethoxybenzene conversion, varying temperature, reaction time, and catalyst load. The optimal conditions that maximized the phenethoxybenzene conversion were 137 °C, 3.5 h, and 200 mg of catalyst. In addition, under the optimized conditions, the Kraft ligniMolecules (Basel, Switzerland)Catalytic Selective Oxidation of β-O-4 Bond in Phenethoxybenzene as a Lignin Model Using (TBA)₅[PMo₁₀V₂O₄₀] Nanocatalyst: Optimization of Operational Conditions.PMC104901831201895Campos CHMelin VAzocar LContreras DDiaz JPizzio LRBriones RPecchi GMurillo-Sierra JCRomero RTroncoso EMendez-Rivas CfalseCatalytic Selective Oxidation of β-O-4 Bond in Phenethoxybenzene as a Lignin Model Using (TBA)₅[PMo₁₀V₂O₄₀] Nanocatalyst: Optimization of Operational Conditions.The catalytic oxidation of phenethoxybenzene as a lignin model compound with a β-O-4 bond was conducted using the Keggin-type polyoxometalate nanocatalyst (TBA)₅[PMo₁₀V₂O₄₀]. The optimization of the process's operational conditions was carried out using response surface methodology. The statistically significant variables in the process were determined using a fractional factorial design. Based on this selection, a central circumscribed composite experimental design was used to maximize the phenethoxybenzene conversion, varying temperature, reaction time, and catalyst load. The optimal conditions that maximized the phenethoxybenzene conversion were 137 °C, 3.5 h, and 200 mg of catalyst. In addition, under the optimized conditions, the Kraft ligni2023-01-01T00:00:00Z2023 Aug2025-04-04T03:19:15.582Z2025-02-19T01:55:39.002ZS-EPMC104901833768719710.3390/molecules28176368