{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Peng CC"],"funding":["European Research Council","Deutsche Forschungsgemeinschaft"],"pagination":["27520-27524"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10501047"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(39)"],"pubmed_abstract":["The choanoflagellate <i>Salpingoeca rosetta</i> transitions from unicellular to multicellular forms in the presence of bacterial signaling molecules, such as sulfonosphingolipids (RIFs). We set out to characterize the abundance of RIF-like molecules within five different Bacteroidetes strains belonging to different genera. While four strains exhibited similar sulfonosphingolipid profiles with sulfobacin A as the dominant feature, the composition in <i>Z. uliginosa</i> differed distinctively. Targeted isolation yielded four sulfonosphingolipids, including the previously reported flavocristamide A. While none of the sulfonosphingolipids induced rosette formation, a negative impact on choanoflagellate growth and cell density was observed. In contrast, supernatant extracts of <i>Zobellia</i> d"],"journal":["RSC advances"],"pubmed_title":["Isolation of sulfonosphingolipids from the rosette-inducing bacterium <i>Zobellia uliginosa</i> and evaluation of their rosette-inducing activity."],"pmcid":["PMC10501047"],"funding_grant_id":["BE 4799/2-1","802736"],"pubmed_authors":["Dormanns N","Peng CC","Beemelmanns C","Regestein L"],"additional_accession":[]},"is_claimable":false,"name":"Isolation of sulfonosphingolipids from the rosette-inducing bacterium <i>Zobellia uliginosa</i> and evaluation of their rosette-inducing activity.","description":"The choanoflagellate <i>Salpingoeca rosetta</i> transitions from unicellular to multicellular forms in the presence of bacterial signaling molecules, such as sulfonosphingolipids (RIFs). We set out to characterize the abundance of RIF-like molecules within five different Bacteroidetes strains belonging to different genera. While four strains exhibited similar sulfonosphingolipid profiles with sulfobacin A as the dominant feature, the composition in <i>Z. uliginosa</i> differed distinctively. Targeted isolation yielded four sulfonosphingolipids, including the previously reported flavocristamide A. While none of the sulfonosphingolipids induced rosette formation, a negative impact on choanoflagellate growth and cell density was observed. In contrast, supernatant extracts of <i>Zobellia</i> d","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2025-04-06T18:32:25.577Z","creation":"2025-04-06T18:32:25.577Z"},"accession":"S-EPMC10501047","cross_references":{"pubmed":["37720827"],"doi":["10.1039/d3ra04314b"]}}