{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Griffeth EM"],"funding":["National Heart, Lung, and Blood Institute","NHLBI NIH HHS","National Institutes of Health"],"pagination":["499-507"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10524729"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["116(3)"],"pubmed_abstract":["<h4>Background</h4>Little data exist regarding characteristics and outcomes of pediatric patients undergoing septal myectomy. We evaluated this in a large referral population.<h4>Methods</h4>Septal myectomy was performed in 199 consecutive patients aged ≤18 years with obstructive hypertrophic cardiomyopathy from January 1, 1976, to June 30, 2021.<h4>Results</h4>Median age was 13 years (interquartile range [IQR], 8-15 years). Left ventricular myectomy approaches included transaortic (163 of 198 [82%]), transapical (16 of 198 [8%]), and combined (19 of 198 [10%]). Right ventricular interventions included myectomy (13 of 199 [7%]) and patch reconstruction of the outflow tract (15 of 199 [8%]). Maximum left ventricular outflow tract gradients decreased after myectomy (prebypass: 50 mm Hg [IQR,"],"journal":["The Annals of thoracic surgery"],"pubmed_title":["Septal Myectomy Outcomes in Children and Adolescents With Obstructive Hypertrophic Cardiomyopathy."],"pmcid":["PMC10524729"],"funding_grant_id":["R38HL150086","R38 HL150086"],"pubmed_authors":["Ackerman MJ","Stephens EH","Alzate-Aguirre M","Dearani JA","Johnson JN","Wackel PL","Cannon BC","Schaff HV","Bos JM","Todd A","Griffeth EM"],"additional_accession":[]},"is_claimable":false,"name":"Septal Myectomy Outcomes in Children and Adolescents With Obstructive Hypertrophic Cardiomyopathy.","description":"<h4>Background</h4>Little data exist regarding characteristics and outcomes of pediatric patients undergoing septal myectomy. We evaluated this in a large referral population.<h4>Methods</h4>Septal myectomy was performed in 199 consecutive patients aged ≤18 years with obstructive hypertrophic cardiomyopathy from January 1, 1976, to June 30, 2021.<h4>Results</h4>Median age was 13 years (interquartile range [IQR], 8-15 years). Left ventricular myectomy approaches included transaortic (163 of 198 [82%]), transapical (16 of 198 [8%]), and combined (19 of 198 [10%]). Right ventricular interventions included myectomy (13 of 199 [7%]) and patch reconstruction of the outflow tract (15 of 199 [8%]). Maximum left ventricular outflow tract gradients decreased after myectomy (prebypass: 50 mm Hg [IQR,","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2025-04-19T01:42:49.943Z","creation":"2025-04-07T12:26:10.15Z"},"accession":"S-EPMC10524729","cross_references":{"pubmed":["37116851"],"doi":["10.1016/j.athoracsur.2023.04.021"]}}