biostudies-literatureGriffeth EMNational Heart, Lung, and Blood InstituteNHLBI NIH HHSNational Institutes of Health499-507https://www.ebi.ac.uk/biostudies/studies/S-EPMC10524729biostudies-literatureUnknown116(3)<h4>Background</h4>Little data exist regarding characteristics and outcomes of pediatric patients undergoing septal myectomy. We evaluated this in a large referral population.<h4>Methods</h4>Septal myectomy was performed in 199 consecutive patients aged ≤18 years with obstructive hypertrophic cardiomyopathy from January 1, 1976, to June 30, 2021.<h4>Results</h4>Median age was 13 years (interquartile range [IQR], 8-15 years). Left ventricular myectomy approaches included transaortic (163 of 198 [82%]), transapical (16 of 198 [8%]), and combined (19 of 198 [10%]). Right ventricular interventions included myectomy (13 of 199 [7%]) and patch reconstruction of the outflow tract (15 of 199 [8%]). Maximum left ventricular outflow tract gradients decreased after myectomy (prebypass: 50 mm Hg [IQR,The Annals of thoracic surgerySeptal Myectomy Outcomes in Children and Adolescents With Obstructive Hypertrophic Cardiomyopathy.PMC10524729R38HL150086R38 HL150086Ackerman MJStephens EHAlzate-Aguirre MDearani JAJohnson JNWackel PLCannon BCSchaff HVBos JMTodd AGriffeth EMfalseSeptal Myectomy Outcomes in Children and Adolescents With Obstructive Hypertrophic Cardiomyopathy.<h4>Background</h4>Little data exist regarding characteristics and outcomes of pediatric patients undergoing septal myectomy. We evaluated this in a large referral population.<h4>Methods</h4>Septal myectomy was performed in 199 consecutive patients aged ≤18 years with obstructive hypertrophic cardiomyopathy from January 1, 1976, to June 30, 2021.<h4>Results</h4>Median age was 13 years (interquartile range [IQR], 8-15 years). Left ventricular myectomy approaches included transaortic (163 of 198 [82%]), transapical (16 of 198 [8%]), and combined (19 of 198 [10%]). Right ventricular interventions included myectomy (13 of 199 [7%]) and patch reconstruction of the outflow tract (15 of 199 [8%]). Maximum left ventricular outflow tract gradients decreased after myectomy (prebypass: 50 mm Hg [IQR,2023-01-01T00:00:00Z2023 Sep2025-04-19T01:42:49.943Z2025-04-07T12:26:10.15ZS-EPMC105247293711685110.1016/j.athoracsur.2023.04.021