{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stoyanova K"],"funding":["The Bulgarian National Science Fund within national project: \"COVID-19 HUB - Information, Innovations and Implementation of Integrative Scientific Developments\""],"pagination":["1271"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10526257"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(9)"],"pubmed_abstract":["The first epidemiological wave of the incidence of COVID-19 in Bulgaria was registered in June 2020. After the wave peak, we conducted a study in persons diagnosed with COVID-19 (N = 52). They were assessed with the anxiety-depressive scale (ADS), including basic (BS), vegetative (VS), conversion (CS), obsessive-phobic (OPS), and depressive (DS) symptoms. ADS assessment of individuals diagnosed with SARS-CoV-2 indicated a correlation between OPS and IL-33 values. IL-10 levels were higher than reference ranges in all patients. Multiple linear regression analyses demonstrated that combination of CS and OPS explained 28% of IL-33 levels, while combination of symptoms from all ADS dimensions explained 24% of IL-33 levels. It was also found that 21% of IL-28A levels was explained from the combination by all ADS dimensions, whereas OPS was the predictor for lower concentrations. The obtained results revealed meaningful correlations between psycho neuro-immunological factors in pathogenesis of illness from the coronavirus infection."],"journal":["Brain sciences"],"pubmed_title":["Conversion and Obsessive-Phobic Symptoms Predict IL-33 and IL-28A Levels in Individuals Diagnosed with COVID-19."],"pmcid":["PMC10526257"],"funding_grant_id":["Contract No. KP-06-DK1/6 from 29/03/2021"],"pubmed_authors":["Taskov H","Stoyanova K","Vassilev P","Murdzheva M","Andreeva H","Baldzhieva A","Bozhkova M","Stoyanov D","Petrov S","Todev A","Kalfova T"],"additional_accession":[]},"is_claimable":false,"name":"Conversion and Obsessive-Phobic Symptoms Predict IL-33 and IL-28A Levels in Individuals Diagnosed with COVID-19.","description":"The first epidemiological wave of the incidence of COVID-19 in Bulgaria was registered in June 2020. After the wave peak, we conducted a study in persons diagnosed with COVID-19 (N = 52). They were assessed with the anxiety-depressive scale (ADS), including basic (BS), vegetative (VS), conversion (CS), obsessive-phobic (OPS), and depressive (DS) symptoms. ADS assessment of individuals diagnosed with SARS-CoV-2 indicated a correlation between OPS and IL-33 values. IL-10 levels were higher than reference ranges in all patients. Multiple linear regression analyses demonstrated that combination of CS and OPS explained 28% of IL-33 levels, while combination of symptoms from all ADS dimensions explained 24% of IL-33 levels. It was also found that 21% of IL-28A levels was explained from the combination by all ADS dimensions, whereas OPS was the predictor for lower concentrations. The obtained results revealed meaningful correlations between psycho neuro-immunological factors in pathogenesis of illness from the coronavirus infection.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-04-05T09:43:15.996Z","creation":"2025-04-05T09:43:15.996Z"},"accession":"S-EPMC10526257","cross_references":{"pubmed":["37759873"],"doi":["10.3390/brainsci13091271"]}}