biostudies-literatureShin YHNIA NIH HHSNational Institute for Health Research (NIHR)National Research Foundation of KoreaBill and Melinda Gates Foundation2232-2254https://www.ebi.ac.uk/biostudies/studies/S-EPMC10529296biostudies-literatureUnknown78(8)<h4>Background</h4>Asthma and atopic dermatitis (AD) are chronic allergic conditions, along with allergic rhinitis and food allergy and cause high morbidity and mortality both in children and adults. This study aims to evaluate the global, regional, national, and temporal trends of the burden of asthma and AD from 1990 to 2019 and analyze their associations with geographic, demographic, social, and clinical factors.<h4>Methods</h4>Using data from the Global Burden of Diseases (GBD), Injuries, and Risk Factors Study 2019, we assessed the age-standardized prevalence, incidence, mortality, and disability-adjusted life years (DALYs) of both asthma and AD from 1990 to 2019, stratified by geographic region, age, sex, and socio-demographic index (SDI). DALYs were calculated as the sum of years liAllergyGlobal, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019.PMC10529296P01 AG017625NIHR202425Mallhi THAboagye RGMohammed SMalta DCCarr SDemeke DAdane DEAMokdad AHZenebe GAGhadirian FIwu CCDRahman MAKutikuppala LVSMedina JRCMustafa GOkati-Aliabad HPatel JKibret BGLopes GRam PBanach MHossain MSBajbouj KShanawaz MHwang BFMomtazmanesh SFeng XKhader YSZar HJRabiee NHassen MBNzoputam OJEkundayo TCFakhradiyev IRGolechha MFagbamigbe AFMunblit DGizaw ATRao IRKabir ZGoleij PMonasta LRahmanian VHolla RRomero-Rodriguez ESibhat MMZare IRonfani LNazari JSheikh AHeibati BSaya GKAddo IYSaad AMASantric-Milicevic MMOlufadewa IIAtlaw DKhajuria HKoyanagi AElmeligy OAATalaat IMHorita NBardhan MNg TPLauriola PFatima SAFTesler RZhao HRawal LAlvis-Guzman NChu DTGupta SLo CHAlif SMKompani FAdane TDLigade VSHalwani RDadras OKoul PAPereira MEkholuenetale MFukumoto TUpadhyay EAshraf TCamargos PZhang ZJKaur HPodder IUllah SAnsar AOancea BYu CLee SWTillawi TMishra MUllah IAbdelmasseh MMenezes RGKeykhaei MDandona RRodriguez JABShin YHKeikavoosi-Arani LKisa SPadubidri JRLinda Merin JTemsah MHForoutan MAbdulah DMBabamohamadi HHashi AKuttikkattu ANguyen VTSharif-Askari FSHasani HSalehi SDamiani GMirrakhimov EMKisa ARahimi MCruz-Martins NSajid MRRoever LEsubalew HKantar RSVos TFatehizadeh AElhadi MSaeed ULi MCSaddik BMaharaj SBRahmani SLee YHVasankari TJArulappan JDiress MPereira RBLi SWilliams HCAbate YHSarkhosh MDandona LLarijani BIspayeva ZBIZBEtaee FAsghari-Jafarabadi MTan KKAbtew YDNatto ZSKarimi HSalahi SMestrovic TCai JDemisse BTamuzi JJLLTicoalu JHVBhat ANGhamari SHMulugeta TLiu WVerras GILiu XThangaraju PTusa BSShin JIBagherieh SHannan MAWesterman RBashiri ANguyen DHMahalingam SZeineddine MASahoo HPandey ARawaf SSahebkar AAbrams EMZastrozhin MSNouraei HShobeiri PBerhie AYHwang JAzadnajafabad SCharalampous PKaraye IMMasoumi SZBadawi ABhojaraja VSZahir MKhan IARajput PTerefa DRRedwan EMMCar JIsmail NEMensah GAAbbasi-Kangevari ZShah HKolkhir PMinh LHNSamy AMSoshnikov SGBD 2019 Allergic Disorders CollaboratorsBijani AOkwute PGBaghcheghi NChattu VKKhatatbeh MMKorzh OAbbasi-Kangevari MAhmed ARamasubramani PSkryabina AAIlic MDSingh JAMahmoud MAAdibi AKandel HBarrow AYonemoto NNassereldine HMisganaw ARezaei NIrilouzadian RShorofi SAAlipour VAthari SSAujayeb AAdha RHeidari GMalekpour MRObaidur RMPetcu IRSolomon YHeidari MJebai RRezaei SAhmadi AAl-Azzam SGupta VKGizaw ABARahmani AMFischer FGela YYTran MTNDongarwar DKim MSJajarmi MJanodia MDSakshaug JWAbu-Gharbieh EBensenor IMHeidari-Foroozan MKhanal SNair TSDai XMentis AAGaipov AKurmi OPFerreira NKumar GAYismaw YMohammad APChakraborty PABarone-Adesi FMaugeri AIlic IMSenthilkumaran SKwon RSteiropoulos PNayak BPOrru HEtemadimanesh ARavikumar NShekhar SAgrawal AChan JSKChowdhury MAKMichalek IMNangia VJayaram SMurillo-Zamora EAdnani QESHaj-Mirzaian AKhan MAPatthipati VSYon DKLe TTTPodder VAhmad SKaliyadan FQattea IBhagavathula ASBikov AJamshidi EPark EKPaudel UOkonji OCSimpson CRPatil SHussain SRezaeian MSarasmita MAShigematsu MSingh PSingh SMalik AAGillum RFSingh VPardhan SBabaei MBayileyegn NSYunusa ILatief KRegmi ARKhubchandani JRahman MFetensa GAltirkawi KACarugno AKoohestani HRSagoe DLim SSDiaz DVahabi SMSiraj MSAlhalaiqa FANVieira RJCorso Bvan Boven JFMMahesh PAGoldust MKrishan KRatan ZAYada DYAbolhassani HNiazi RKSwamy SNMoniruzzaman MSong SKaambwa BKuehni CEChashmyazdan MShaikh MAFereidouni MOlagunju ATGhozy STat NYWickramasinghe NDHamidi SHasaballah AISoyiri INAltaany ZObsa AGAly HBhardwaj PZoladl MBeyene KALenzi JMamun AAKhan MJonas JBJoseph NSzeto MDMajeed ARashid AMLam JViolante FSfalseGlobal, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019.<h4>Background</h4>Asthma and atopic dermatitis (AD) are chronic allergic conditions, along with allergic rhinitis and food allergy and cause high morbidity and mortality both in children and adults. This study aims to evaluate the global, regional, national, and temporal trends of the burden of asthma and AD from 1990 to 2019 and analyze their associations with geographic, demographic, social, and clinical factors.<h4>Methods</h4>Using data from the Global Burden of Diseases (GBD), Injuries, and Risk Factors Study 2019, we assessed the age-standardized prevalence, incidence, mortality, and disability-adjusted life years (DALYs) of both asthma and AD from 1990 to 2019, stratified by geographic region, age, sex, and socio-demographic index (SDI). DALYs were calculated as the sum of years li2023-01-01T00:00:00Z2023 Aug2026-03-31T11:04:55.488Z2025-08-27T03:11:21.885ZS-EPMC105292963743185310.1111/all.15807