biostudies-literatureLopez-Alarcon MConsejo Nacional de Ciencia y Tecnología1319https://www.ebi.ac.uk/biostudies/studies/S-EPMC10533085biostudies-literatureUnknown13(9)Polycystic ovary syndrome (PCOS) is often accompanied with metabolic disturbances attributed to androgen excess and obesity, but the contribution of each has not been defined, and the occurrence of metabolic disturbances is usually not investigated. Ninety-nine women with PCOS and forty-one without PCOS were evaluated. The clinical biomarkers of alterations related to glucose (glucose, insulin, and clamp-derived glucose disposal - <i>M</i>), liver (aspartate aminotransferase, alanine aminotransferase, and gamma-glutamyl transferase), and endothelium (arginine, asymmetric dymethylarginine, carotid intima-media thickness, and flow-mediated dilation) metabolism were measured; participants were categorized into four groups according to their obesity (OB) and hyperandrogenemia (HA) status as foJournal of personalized medicineObesity and Hyperandrogenemia in Polycystic Ovary Syndrome: Clinical Implications.PMC10533085FOSSIS 2017-1-290399Lopez-Alarcon MBarradas-Vazquez ASVital-Reyes VSCruz-Martinez DDominguez-Salgado JMZ'Cruz-Lopez RAlmeida-Gutierrez EMaldonado-Hernandez JFlores-Chavez SVite-Bautista JfalseObesity and Hyperandrogenemia in Polycystic Ovary Syndrome: Clinical Implications.Polycystic ovary syndrome (PCOS) is often accompanied with metabolic disturbances attributed to androgen excess and obesity, but the contribution of each has not been defined, and the occurrence of metabolic disturbances is usually not investigated. Ninety-nine women with PCOS and forty-one without PCOS were evaluated. The clinical biomarkers of alterations related to glucose (glucose, insulin, and clamp-derived glucose disposal - <i>M</i>), liver (aspartate aminotransferase, alanine aminotransferase, and gamma-glutamyl transferase), and endothelium (arginine, asymmetric dymethylarginine, carotid intima-media thickness, and flow-mediated dilation) metabolism were measured; participants were categorized into four groups according to their obesity (OB) and hyperandrogenemia (HA) status as fo2023-01-01T00:00:00Z2023 Aug2025-04-18T14:47:45.48Z2025-02-19T00:10:35.049ZS-EPMC105330853776308710.3390/jpm13091319