{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Delgado-Garcia M"],"funding":["Consejo Nacional de Ciencia y Tecnología","CONACYT"],"pagination":["2344"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10537243"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(9)"],"pubmed_abstract":["Natural pigments from haloarchaea are of great interest; bacterioruberin is the major pigment, it shows higher antioxidant power when compared with β-carotene. However, characterization of bacterioruberin and its isomers along with its antioxidant and the matrix metallopeptidase 9 (MMP-9) inhibition activities in extracts from <i>Natronoccoccus</i> sp. TC6 and <i>Halorubrum tebenquichense</i> SU10 was not previously described, being the aim of this work. The carotenoids profile was performed by UV-Vis spectrophotometry, thin-layer chromatography, nuclear magnetic resonance spectroscopy, and high-resolution mass spectrometry (UPLC-ESI-MS/MS). Antioxidant capacity was determined for DPPH, ABTS, and FRAP. In addition, MMP-9 inhibition was studied using docking simulations. The carotenoid prof"],"journal":["Microorganisms"],"pubmed_title":["Identification, Antioxidant Capacity, and Matrix Metallopeptidase 9 (MMP-9) In Silico Inhibition of Haloarchaeal Carotenoids from <i>Natronococcus</i> sp. and <i>Halorubrum tebenquichense</i>."],"pmcid":["PMC10537243"],"funding_grant_id":["423456","CVU 423456"],"pubmed_authors":["Rodriguez JA","Aguilar CN","Mateos-Diaz JC","Delgado-Garcia M","Muller-Santos M","Gomez-Secundino O","Camacho-Ruiz RM"],"additional_accession":[]},"is_claimable":false,"name":"Identification, Antioxidant Capacity, and Matrix Metallopeptidase 9 (MMP-9) In Silico Inhibition of Haloarchaeal Carotenoids from <i>Natronococcus</i> sp. and <i>Halorubrum tebenquichense</i>.","description":"Natural pigments from haloarchaea are of great interest; bacterioruberin is the major pigment, it shows higher antioxidant power when compared with β-carotene. However, characterization of bacterioruberin and its isomers along with its antioxidant and the matrix metallopeptidase 9 (MMP-9) inhibition activities in extracts from <i>Natronoccoccus</i> sp. TC6 and <i>Halorubrum tebenquichense</i> SU10 was not previously described, being the aim of this work. The carotenoids profile was performed by UV-Vis spectrophotometry, thin-layer chromatography, nuclear magnetic resonance spectroscopy, and high-resolution mass spectrometry (UPLC-ESI-MS/MS). Antioxidant capacity was determined for DPPH, ABTS, and FRAP. In addition, MMP-9 inhibition was studied using docking simulations. The carotenoid prof","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2026-05-13T14:38:25.804Z","creation":"2025-02-19T00:01:14.793Z"},"accession":"S-EPMC10537243","cross_references":{"pubmed":["37764188"],"doi":["10.3390/microorganisms11092344"]}}