biostudies-literatureClouthier SManitoba Hydro and Fisheries and Oceans CanadaManitoba HydroFisheries &amp;amp; Oceans Canada (DFO/Manitoba Hydro Collaborative Agreement “Sturgeon herpesvirus genetics, phylogeny, ecology and qPCR tests”)1115https://www.ebi.ac.uk/biostudies/studies/S-EPMC10537993biostudies-literatureUnknown12(9)Herpesvirus infections of sturgeon pose a potential threat to sturgeon culture efforts worldwide. A new epitheliotropic herpesvirus named Acipenser herpesvirus 3 (AciHV-3) was detected in hatchery-reared Lake Sturgeon <i>Acipenser fulvescens</i> displaying skin lesions in central Canada. The growths were discovered in the fall, reached average prevalence levels of 0.2-40% and eventually regressed. No unusual mortality was observed. The cellular changes within the lesions included epithelial hyperplasia and were reminiscent of other herpesvirus infections. The virus was not evident in lesions examined by electron microscopy. Skin tissue homogenates from symptomatic sturgeon produced atypical cytopathic effects on a primary Lake Sturgeon cell line, and next-generation sequence analysis of thPathogens (Basel, Switzerland)A New Sturgeon Herpesvirus from Juvenile Lake Sturgeon <i>Acipenser fulvescens</i> Displaying Epithelial Skin Lesions.PMC10537993Collaborative Agreement4500392641Emmenegger ENalpathamkalam TThiruvahindrapuram BTomczyk MKlassen CClouthier SSchroeder TDufresne AWang ZfalseA New Sturgeon Herpesvirus from Juvenile Lake Sturgeon <i>Acipenser fulvescens</i> Displaying Epithelial Skin Lesions.Herpesvirus infections of sturgeon pose a potential threat to sturgeon culture efforts worldwide. A new epitheliotropic herpesvirus named Acipenser herpesvirus 3 (AciHV-3) was detected in hatchery-reared Lake Sturgeon <i>Acipenser fulvescens</i> displaying skin lesions in central Canada. The growths were discovered in the fall, reached average prevalence levels of 0.2-40% and eventually regressed. No unusual mortality was observed. The cellular changes within the lesions included epithelial hyperplasia and were reminiscent of other herpesvirus infections. The virus was not evident in lesions examined by electron microscopy. Skin tissue homogenates from symptomatic sturgeon produced atypical cytopathic effects on a primary Lake Sturgeon cell line, and next-generation sequence analysis of th2023-01-01T00:00:00Z2023 Aug2026-04-07T15:55:14.655Z2025-02-19T01:20:07.922ZS-EPMC105379933776492310.3390/pathogens12091115