{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Guo T"],"funding":["National Natural Science Foundation of China","National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["6076"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10539282"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["One-pot synthesis of heterocyclic aromatics with good optical properties from phenolic β-O-4 lignin segments is of high importance to meet high value added biorefinery demands. However, executing this process remains a huge challenge due to the incompatible reaction conditions of the depolymerization of lignin β-O-4 segments containing γ-OH functionalities and bioresource-based aggregation-induced emission luminogens (BioAIEgens) formation with the desired properties. In this work, benzannulation reactions starting from lignin β-O-4 moieties with 3-alkenylated indoles catalyzed by vanadium-based complexes have been successfully developed, affording a wide range of functionalized carbazoles with up to 92% yield. Experiments and density functional theory calculations suggest that the reactio"],"journal":["Nature communications"],"pubmed_title":["Towards bioresource-based aggregation-induced emission luminogens from lignin β-O-4 motifs as renewable resources."],"pmcid":["PMC10539282"],"funding_grant_id":["22078317","21601087","22108272","22073066"],"pubmed_authors":["Cai XM","Zhang T","Pan D","Huang G","Zhang X","Xu D","Kuhn FE","Guo T","Lin Y","Zhu W","Wang H","Zhang B"],"additional_accession":[]},"is_claimable":false,"name":"Towards bioresource-based aggregation-induced emission luminogens from lignin β-O-4 motifs as renewable resources.","description":"One-pot synthesis of heterocyclic aromatics with good optical properties from phenolic β-O-4 lignin segments is of high importance to meet high value added biorefinery demands. However, executing this process remains a huge challenge due to the incompatible reaction conditions of the depolymerization of lignin β-O-4 segments containing γ-OH functionalities and bioresource-based aggregation-induced emission luminogens (BioAIEgens) formation with the desired properties. In this work, benzannulation reactions starting from lignin β-O-4 moieties with 3-alkenylated indoles catalyzed by vanadium-based complexes have been successfully developed, affording a wide range of functionalized carbazoles with up to 92% yield. Experiments and density functional theory calculations suggest that the reactio","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2025-04-04T18:35:57.502Z","creation":"2025-04-04T18:35:57.502Z"},"accession":"S-EPMC10539282","cross_references":{"pubmed":["37770462"],"doi":["10.1038/s41467-023-41681-0"]}}