{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["36(7)"],"submitter":["Bouwmans P"],"funding":["Dirinco","Eurocept Homecare","Cablon Medical","Bayer","Nierstichting","AstraZeneca","ZonMw","Fresenius Medical Care Deutschland GmbH","CSL Vifor","Novartis","Baxter Nederland"],"pubmed_abstract":["<h4>Background</h4>The mental health of dialysis patients during the COVID-19 pandemic may have been modulated by dialysis modality. Studies comparing mental health of in-center hemodialysis and peritoneal dialysis patients during the first 2 years of the pandemic are lacking.<h4>Methods</h4>We conducted repeated cross-sectional and multivariable regression analyses to compare the mental health of in-center hemodialysis and peritoneal dialysis patients from March 2019 until August 2021 using data from the Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes. The study period was divided into one pre-pandemic and six 3-month pandemic periods (period 1-period 6). Mental health was assessed with the Mental Component Summary score of the 12-item Short Form health survey and mental symptoms of the Dialysis Symptom Index.<h4>Results</h4>We included 1274 patients (968 on in-center hemodialysis and 306 on peritoneal dialysis). Mental Component Summary scores did not differ between in-center hemodialysis and peritoneal dialysis patients. In contrast, in-center hemodialysis patients more often reported nervousness during period 3 (27% vs 15%, P = 0.04), irritability and anxiety during period 3 (31% vs 18%, P = 0.03, 26% vs. 9%, P = 0.002, respectively) and period 4 (34% vs 22%, P = 0.04, 22% vs 11%, P = 0.03, respectively), and sadness in period 4 (38% vs 26%, P = 0.04) and period 5 (37% vs 22%, P = 0.009). Dialysis modality was independently associated with mental symptoms.<h4>Conclusions</h4>In-center hemodialysis patients more often experienced mental symptoms compared to peritoneal dialysis patients from September 2020 to June 2021, which corresponds to the second lockdown of the COVID-19 pandemic. Mental health-related quality-of-life did not differ between in-center hemodialysis and peritoneal dialysis patients.<h4>Trial registration number</h4>Netherlands Trial Register NL6519, date of registration: 22 August, 2017."],"journal":["Journal of nephrology"],"pagination":["2037-2046"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10543747"],"repository":["biostudies-literature"],"pubmed_title":["Differences in mental health status during the COVID-19 pandemic between patients undergoing in-center hemodialysis and peritoneal dialysis."],"pmcid":["PMC10543747"],"pubmed_authors":["Boorsma S","Nette RW","Neradova A","Konijn WS","Klaassen RJL","IJpelaar DHT","Francois K","Susanto CR","Vermeeren YM","Wijering RMJ","Bosma RJ","Hemmelder MH","Dekker FW","Verhoeven MAM","Cnossen TT","van der Net JB","Verhaar MC","Adema AY","Verhave JC","Lips J","Luik AJ","Ozyilmaz A","van Breda GF","Kuijper A","Lips A","Severs D","van Eck van der Sluijs A","Mulder J","van Buren M","van Hamersvelt HW","Dekker MMG","Konijn W","Konings CJAM","Bos WJW","Diepeveen SHA","van Kempen G","Rotmans JI","Schrander-Vd Meer AM","Hofstra JM","Ruger W","Bouwmans P","Mui KW","de Fijter CWH","Klein HHTI","Roeterdink AJ","van Esch S","Weenink AG","Litjens EJR","Vernooij RWM","van Ittersum FJ","Cornelis T","van Alphen AM","Bierma L","DOMESTICO study group","Driehuis E","van Lieshout TS","Snoep JD","van der Meijden WAG","Korte MR","Beerenhout CH","Leurs PB","Boonstra AH","Bonenkamp AA","Krepel HP","Hommes NH","Hoorn EJ","Abrahams AC","De Vriese A","Boereboom FTJ","van Tellingen A","Binnenmars SH","Penne EL","Douma CE","Krekels MME","Huisman SJ","Brulez HFH","van Jaarsveld BC","Hoogeveen EK","Skalli Z","Janssen WMT","Franssen CFM","Ten Dam MAGJ"],"additional_accession":[]},"is_claimable":false,"name":"Differences in mental health status during the COVID-19 pandemic between patients undergoing in-center hemodialysis and peritoneal dialysis.","description":"<h4>Background</h4>The mental health of dialysis patients during the COVID-19 pandemic may have been modulated by dialysis modality. Studies comparing mental health of in-center hemodialysis and peritoneal dialysis patients during the first 2 years of the pandemic are lacking.<h4>Methods</h4>We conducted repeated cross-sectional and multivariable regression analyses to compare the mental health of in-center hemodialysis and peritoneal dialysis patients from March 2019 until August 2021 using data from the Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes. The study period was divided into one pre-pandemic and six 3-month pandemic periods (period 1-period 6). Mental health was assessed with the Mental Component Summary score of the 12-item Short Form health survey and mental symptoms of the Dialysis Symptom Index.<h4>Results</h4>We included 1274 patients (968 on in-center hemodialysis and 306 on peritoneal dialysis). Mental Component Summary scores did not differ between in-center hemodialysis and peritoneal dialysis patients. In contrast, in-center hemodialysis patients more often reported nervousness during period 3 (27% vs 15%, P = 0.04), irritability and anxiety during period 3 (31% vs 18%, P = 0.03, 26% vs. 9%, P = 0.002, respectively) and period 4 (34% vs 22%, P = 0.04, 22% vs 11%, P = 0.03, respectively), and sadness in period 4 (38% vs 26%, P = 0.04) and period 5 (37% vs 22%, P = 0.009). Dialysis modality was independently associated with mental symptoms.<h4>Conclusions</h4>In-center hemodialysis patients more often experienced mental symptoms compared to peritoneal dialysis patients from September 2020 to June 2021, which corresponds to the second lockdown of the COVID-19 pandemic. Mental health-related quality-of-life did not differ between in-center hemodialysis and peritoneal dialysis patients.<h4>Trial registration number</h4>Netherlands Trial Register NL6519, date of registration: 22 August, 2017.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2026-06-01T21:31:11.809Z","creation":"2025-02-18T23:59:45.023Z"},"accession":"S-EPMC10543747","cross_references":{"pubmed":["37606844"],"doi":["10.1007/s40620-023-01747-0"]}}