biostudies-literatureSaleh AAMinistry of EducationNational Research Foundation of KoreaKafrelsheikh UniversityKing Saud University103051https://www.ebi.ac.uk/biostudies/studies/S-EPMC10550832biostudies-literatureUnknown102(11)Global warming and climate changes have a detrimental impact on poultry production, causing substantial economic losses. This study investigated the effects of incorporating dietary betaine (BT) and organic minerals (OMs) on broilers' performance as well as their potential to mitigate the negative impacts of heat stress (HS). Six hundred 1-day-old Ross 308 chicks were randomly allocated to 12 experimental treatments with 5 replicates of 10 birds each (5 male + 5 female). The birds were provided with diets containing BT (0 and 2,000 ppm) and OMs (0, 250, and 500 ppm), either individually or in combination, under both thermoneutral and HS-inducing temperatures. The HS conditions involved exposing the birds to cyclic periods of elevated temperature (35°C ± 2°C) for 6 h daily, from 10:00 am toPoultry scienceEffect of dietary supplementation of betaine and organic minerals on growth performance, serum biochemical parameters, nutrients digestibility, and growth-related genes in broilers under heat stress.PMC10550832RSPD2023R581NRF-RS-2023-00275307Genedy SAlzawqari MHKim IHAlwutayd KEbeid TAEl-Tahan HMAlhotan RAAl-Badwi MAAShaban MEl-Keredy AShukry MMorsy WASaleh AAEid Abdel-Moneim AMCho SSewlim Hussein EOfalseEffect of dietary supplementation of betaine and organic minerals on growth performance, serum biochemical parameters, nutrients digestibility, and growth-related genes in broilers under heat stress.Global warming and climate changes have a detrimental impact on poultry production, causing substantial economic losses. This study investigated the effects of incorporating dietary betaine (BT) and organic minerals (OMs) on broilers' performance as well as their potential to mitigate the negative impacts of heat stress (HS). Six hundred 1-day-old Ross 308 chicks were randomly allocated to 12 experimental treatments with 5 replicates of 10 birds each (5 male + 5 female). The birds were provided with diets containing BT (0 and 2,000 ppm) and OMs (0, 250, and 500 ppm), either individually or in combination, under both thermoneutral and HS-inducing temperatures. The HS conditions involved exposing the birds to cyclic periods of elevated temperature (35°C ± 2°C) for 6 h daily, from 10:00 am to2023-01-01T00:00:00Z2023 Aug2025-04-26T01:57:06.175Z2024-11-09T16:25:26.972ZS-EPMC105508323777452010.1016/j.psj.2023.103051