{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li QY"],"funding":["National Natural Science Foundation of China","National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["6366"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10567795"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["The direct and selective coupling of benzenes with aliphatic hydrocarbons is a promising strategy for C(sp<sup>2</sup>)-C(sp<sup>3</sup>) bond formation using readily available starting materials, yet it remains a significant challenge. In this study, we have developed a simplified photochemical system that incorporates catalytic amounts of iron(III) halides as multifunctional reagents and air as a green oxidant to address this synthetic problem. Under mild conditions, the reaction between a strong C(sp<sup>2</sup>)-H bond and a robust C(sp<sup>3</sup>)-H bond has been achieved, affording a broad range of cross-coupling products with high yields and commendable chemo-, site-selectivity. The iron halide acts as a multifunctional reagent that responds to visible light, initiates C-centered r"],"journal":["Nature communications"],"pubmed_title":["Visible light-triggered selective C(sp<sup>2</sup>)-H/C(sp<sup>3</sup>)-H coupling of benzenes with aliphatic hydrocarbons."],"pmcid":["PMC10567795"],"funding_grant_id":["22071206","22371237"],"pubmed_authors":["Cheng S","Huang T","Li QY","Lin YM","Gong L","Yang F","Ye Z"],"additional_accession":[]},"is_claimable":false,"name":"Visible light-triggered selective C(sp<sup>2</sup>)-H/C(sp<sup>3</sup>)-H coupling of benzenes with aliphatic hydrocarbons.","description":"The direct and selective coupling of benzenes with aliphatic hydrocarbons is a promising strategy for C(sp<sup>2</sup>)-C(sp<sup>3</sup>) bond formation using readily available starting materials, yet it remains a significant challenge. In this study, we have developed a simplified photochemical system that incorporates catalytic amounts of iron(III) halides as multifunctional reagents and air as a green oxidant to address this synthetic problem. Under mild conditions, the reaction between a strong C(sp<sup>2</sup>)-H bond and a robust C(sp<sup>3</sup>)-H bond has been achieved, affording a broad range of cross-coupling products with high yields and commendable chemo-, site-selectivity. The iron halide acts as a multifunctional reagent that responds to visible light, initiates C-centered r","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Oct","modification":"2025-04-22T06:50:55.405Z","creation":"2025-04-05T21:55:52.435Z"},"accession":"S-EPMC10567795","cross_references":{"pubmed":["37821440"],"doi":["10.1038/s41467-023-42191-9"]}}