{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Denayer S"],"funding":["Belgische Federale Overheidsdiensten"],"pagination":["e13202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10570899"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(10)"],"pubmed_abstract":["Background
To support the COVID-19 pandemic response, many countries, including Belgium, implemented baseline genomic surveillance (BGS) programs aiming to early detect and characterize new SARS-CoV-2 variants. In parallel, Belgium maintained a sentinel network of six hospitals that samples patients with severe acute respiratory infections (SARI) and integrated SARS-CoV-2 detection within a broader range of respiratory pathogens. We evaluate the ability of the SARI surveillance to monitor general trends and early signals of viral genetic evolution of SARS-CoV-2 and compare it with the BGS as a reference model.Methods
Nine-hundred twenty-five SARS-CoV-2 positive samples from patients fulfilling the Belgian SARI definition between January 2020 and December 2022 were sequenced"],"journal":["Influenza and other respiratory viruses"],"pubmed_title":["Genomic monitoring of SARS-CoV-2 variants using sentinel SARI hospital surveillance."],"pmcid":["PMC10570899"],"funding_grant_id":["SEQ‐COVID19‐LABSURV"],"pubmed_authors":["Cuypers L","Monsieurs B","Delaere B","Bossuyt N","Magerman K","Couvreur S","Denayer S","van Eycken R","Reynders M","Barbezange C","Demuyser T","Sion C","Baele G","van Gucht S","Dufrasne FE","Jouck D","Seyler L","Dellicour S","Hainaut M","Petit E","Andre E","van Nedervelde E","Dauby N","Brondeel R","Houben S","Maes P","Bourgeois M","Lissoir B","Laenen L"],"additional_accession":[]},"is_claimable":false,"name":"Genomic monitoring of SARS-CoV-2 variants using sentinel SARI hospital surveillance.","description":"Background
To support the COVID-19 pandemic response, many countries, including Belgium, implemented baseline genomic surveillance (BGS) programs aiming to early detect and characterize new SARS-CoV-2 variants. In parallel, Belgium maintained a sentinel network of six hospitals that samples patients with severe acute respiratory infections (SARI) and integrated SARS-CoV-2 detection within a broader range of respiratory pathogens. We evaluate the ability of the SARI surveillance to monitor general trends and early signals of viral genetic evolution of SARS-CoV-2 and compare it with the BGS as a reference model.Methods
Nine-hundred twenty-five SARS-CoV-2 positive samples from patients fulfilling the Belgian SARI definition between January 2020 and December 2022 were sequenced","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Oct","modification":"2026-04-29T02:38:09.135Z","creation":"2025-02-19T01:20:13.488Z"},"accession":"S-EPMC10570899","cross_references":{"pubmed":["37840842"],"doi":["10.1111/irv.13202"]}}