{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Yang C"],"funding":["Research Grants Council, University Grants Committee","National Natural Science Fund in China","Shenzhen Key Project for Basic Research"],"pubmed_abstract":["In this work, we collected foodborne <i>Salmonella</i> strains in Shenzhen, China, during 2014-2017 and investigated the genetic profile of all cefotaxime-resistant isolates in the collection. The strains were subjected to antimicrobial susceptibility tests, whole-genome sequencing, bioinformatics analysis, and conjugation studies. A total of 79 cefotaxime-resistant <i>Salmonella</i> were identified and found to exhibit multidrug resistance. Resistance rate recorded during the study period increased from 1.9% to 9.1%. <i>Salmonella</i> Typhimurium was the predominant serovar, and CTX-M family genes were dominant among the ESBLs genes detected. Notably, CTX-M-bearing plasmids or transposons often contain other drug resistance genes. Furthermore, a combination of CTX-M-55 and CTX-M-65 genes "],"journal":["Microbiology spectrum"],"pagination":["e0488622"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10580925"],"repository":["biostudies-literature"],"pubmed_title":["Prevalence and molecular characterization of cefotaxime-resistant <i>Salmonella</i> strains recovered from retail meat samples in Shenzhen, China, during 2014-2017."],"pmcid":["PMC10580925"],"funding_grant_id":["JCYJ20200109143220716","N_PolyU521/18","NSFC-RGC"],"pubmed_authors":["Yang X","Ye L","Heng H","Chen K","Wai-Chi Chan E","Chen S","Yang C"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and molecular characterization of cefotaxime-resistant <i>Salmonella</i> strains recovered from retail meat samples in Shenzhen, China, during 2014-2017.","description":"In this work, we collected foodborne <i>Salmonella</i> strains in Shenzhen, China, during 2014-2017 and investigated the genetic profile of all cefotaxime-resistant isolates in the collection. The strains were subjected to antimicrobial susceptibility tests, whole-genome sequencing, bioinformatics analysis, and conjugation studies. A total of 79 cefotaxime-resistant <i>Salmonella</i> were identified and found to exhibit multidrug resistance. Resistance rate recorded during the study period increased from 1.9% to 9.1%. <i>Salmonella</i> Typhimurium was the predominant serovar, and CTX-M family genes were dominant among the ESBLs genes detected. Notably, CTX-M-bearing plasmids or transposons often contain other drug resistance genes. Furthermore, a combination of CTX-M-55 and CTX-M-65 genes ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2026-05-28T11:14:40.765Z","creation":"2025-04-06T02:09:00.308Z"},"accession":"S-EPMC10580925","cross_references":{"pubmed":["37615439"],"doi":["10.1128/spectrum.04886-22"]}}