biostudies-literatureUnknown16(7)Math PBIn August 2022, the United States Food and Drug Administration issued marketing authorization for an orally administered vibrating colon-stimulating capsule for treating chronic idiopathic constipation. We aimed to review the literature systematically and synthesize evidence on the role of the vibrating capsule in chronic idiopathic constipation. A comprehensive search was conducted on PubMed, Embase, International Clinical Trials Registry Platform (World Health Organization), Cochrane Library databases, and two pre-print servers (medRxiv.org and Research Square) until 31 December 2022, to identify published pre-clinical and clinical original studies evaluating the role of the vibrating capsule in patients with chronic constipation. The studies were critically analyzed, and data were extraJournal of medicine and life1050-1056https://www.ebi.ac.uk/biostudies/studies/S-EPMC10600682biostudies-literatureVibrating colon-stimulating capsule to treat chronic constipation: A systematic review.PMC10600682Math PBPatel NDas SHakami TRavi RfalseVibrating colon-stimulating capsule to treat chronic constipation: A systematic review.In August 2022, the United States Food and Drug Administration issued marketing authorization for an orally administered vibrating colon-stimulating capsule for treating chronic idiopathic constipation. We aimed to review the literature systematically and synthesize evidence on the role of the vibrating capsule in chronic idiopathic constipation. A comprehensive search was conducted on PubMed, Embase, International Clinical Trials Registry Platform (World Health Organization), Cochrane Library databases, and two pre-print servers (medRxiv.org and Research Square) until 31 December 2022, to identify published pre-clinical and clinical original studies evaluating the role of the vibrating capsule in patients with chronic constipation. The studies were critically analyzed, and data were extra2023-01-01T00:00:00Z2023 Jul2025-04-05T11:53:24.176Z2025-04-05T11:53:24.176ZS-EPMC106006823790006210.25122/jml-2023-1025