{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2023"],"submitter":["Pinho-Jr JDS"],"pubmed_abstract":["<h4>Background</h4>Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to cardiovascular diseases (CVDs), hypertension, dyslipidemia, and insulin resistance. Irisin, a protein derived from the cleavage of fibronectin type III domain-containing protein 5, may have relationship with these cardiometabolic diseases.<h4>Objective</h4>This systematic review aims to examine the relationship between serum irisin levels and obesity, particularly in individuals predisposed to cardiovascular risk factors.<h4>Methods</h4>A thorough literature search was conducted in multiple databases, including \"Science Direct,\" \"Scopus,\" \"PubMed,\" and \"Lil"],"journal":["International journal of inflammation"],"pagination":["5810157"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10602702"],"repository":["biostudies-literature"],"pubmed_title":["Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review."],"pmcid":["PMC10602702"],"pubmed_authors":["Cavararo CDS","Medeiros RF","Barroso SG","Pinho-Jr JDS","de Matos AC","Camacho FA","Baiao PF"],"additional_accession":[]},"is_claimable":false,"name":"Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review.","description":"<h4>Background</h4>Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to cardiovascular diseases (CVDs), hypertension, dyslipidemia, and insulin resistance. Irisin, a protein derived from the cleavage of fibronectin type III domain-containing protein 5, may have relationship with these cardiometabolic diseases.<h4>Objective</h4>This systematic review aims to examine the relationship between serum irisin levels and obesity, particularly in individuals predisposed to cardiovascular risk factors.<h4>Methods</h4>A thorough literature search was conducted in multiple databases, including \"Science Direct,\" \"Scopus,\" \"PubMed,\" and \"Lil","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-05T11:54:13.171Z","creation":"2025-04-05T11:54:13.171Z"},"accession":"S-EPMC10602702","cross_references":{"pubmed":["37900979"],"doi":["10.1155/2023/5810157"]}}