{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Miranda KJ"],"funding":["British Council Philippines","Commission on Higher Education"],"pagination":["2563"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10609385"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(10)"],"pubmed_abstract":["Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism, <i>Pseudomonas</i> sp. SST3, from the South Shetland Trough, Antarctica, a co-cultivation with a second deep-sea <i>Pseudomonas zhaodongensis</i> SST2, was undertaken to isolate pseudomonassin, a ribosomally synthesised and post-translationally modified peptide (RiPP) that belongs to a class of RiPP called lasso peptides. Pseudomonassin was identified using a genome-mining approach and isolated by means of mass spectrometric guided isolation. Extensive metabolomics analysis of the co-cultivation of <i>Pseudomonas</i> sp. SST3 and <i>P. zhaodongensis</i> SST2, <i>Pseudomonas</i> sp. "],"journal":["Microorganisms"],"pubmed_title":["Pseudomonassin, a New Bioactive Ribosomally Synthesised and Post-Translationally Modified Peptide from <i>Pseudomonas</i> sp. SST3."],"pmcid":["PMC10609385"],"funding_grant_id":["CHED-British Council Newton Agham Fellowship Grant"],"pubmed_authors":["Edrada-Ebel R","Miranda KJ","Atoum D","Ebel R","Jaspars M","Jaber S","Arjunan S"],"additional_accession":[]},"is_claimable":false,"name":"Pseudomonassin, a New Bioactive Ribosomally Synthesised and Post-Translationally Modified Peptide from <i>Pseudomonas</i> sp. SST3.","description":"Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism, <i>Pseudomonas</i> sp. SST3, from the South Shetland Trough, Antarctica, a co-cultivation with a second deep-sea <i>Pseudomonas zhaodongensis</i> SST2, was undertaken to isolate pseudomonassin, a ribosomally synthesised and post-translationally modified peptide (RiPP) that belongs to a class of RiPP called lasso peptides. Pseudomonassin was identified using a genome-mining approach and isolated by means of mass spectrometric guided isolation. Extensive metabolomics analysis of the co-cultivation of <i>Pseudomonas</i> sp. SST3 and <i>P. zhaodongensis</i> SST2, <i>Pseudomonas</i> sp. ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Oct","modification":"2025-04-25T17:26:42.131Z","creation":"2025-04-06T05:09:57.177Z"},"accession":"S-EPMC10609385","cross_references":{"pubmed":["37894221"],"doi":["10.3390/microorganisms11102563"]}}