biostudies-literatureUnknown47(5)Kwon HE<h4>Objective</h4>: To systematically review the effects of protein supplementation in older adults with sarcopenia.<h4>Methods</h4>: A systematic literature search was conducted in PubMed, Cochrane Library, and Embase databases until May 2023. The inclusion criteria were as follows: (1) randomized controlled trials with a quantitative study design; (2) studies with a study group of older adults with sarcopenia; (3) studies comparing muscle mass, muscle strength, and performance of older adults with sarcopenia after protein supplementation; and (4) studies published up to May 2023.<h4>Results</h4>: Six retrospective comparative studies, including 715 patients, met the inclusion criteria. The nutritional supplementation group exhibited significant improvement in appendicular skeletal muscle mass (standardized mean difference [SMD]=0.41; 95% confidence interval [CI], 0.24-0.58; p<0.001; I²=1%), while handgrip strength (SMD=0.37; 95% CI, -0.32-1.07; p=0.29; I²=94%) and Short Physical Performance Battery (SPPB) (SMD=0.35; 95% CI, -0.47-1.18; p=0.40; I²=94%) showed a tendency for improvement.<h4>Conclusion</h4>: Nutritional supplementation with protein increased appendicular muscle mass in older adults with sarcopenia and improved handgrip strength and SPPB scores.Annals of rehabilitation medicine358-366https://www.ebi.ac.uk/biostudies/studies/S-EPMC10620490biostudies-literatureImproved Muscle Mass and Function With Protein Supplementation in Older Adults With Sarcopenia: A Meta-Analysis.PMC10620490Kwon HEChoi SWKo NKoh SEYuk DfalseImproved Muscle Mass and Function With Protein Supplementation in Older Adults With Sarcopenia: A Meta-Analysis.<h4>Objective</h4>: To systematically review the effects of protein supplementation in older adults with sarcopenia.<h4>Methods</h4>: A systematic literature search was conducted in PubMed, Cochrane Library, and Embase databases until May 2023. The inclusion criteria were as follows: (1) randomized controlled trials with a quantitative study design; (2) studies with a study group of older adults with sarcopenia; (3) studies comparing muscle mass, muscle strength, and performance of older adults with sarcopenia after protein supplementation; and (4) studies published up to May 2023.<h4>Results</h4>: Six retrospective comparative studies, including 715 patients, met the inclusion criteria. The nutritional supplementation group exhibited significant improvement in appendicular skeletal muscle mass (standardized mean difference [SMD]=0.41; 95% confidence interval [CI], 0.24-0.58; p<0.001; I²=1%), while handgrip strength (SMD=0.37; 95% CI, -0.32-1.07; p=0.29; I²=94%) and Short Physical Performance Battery (SPPB) (SMD=0.35; 95% CI, -0.47-1.18; p=0.40; I²=94%) showed a tendency for improvement.<h4>Conclusion</h4>: Nutritional supplementation with protein increased appendicular muscle mass in older adults with sarcopenia and improved handgrip strength and SPPB scores.2023-01-01T00:00:00Z2023 Oct2024-11-14T20:29:49.154Z2024-11-14T20:29:49.154ZS-EPMC106204903790722710.5535/arm.23076