biostudies-literatureFan LResearch Fund of West China Second University HospitalScience and Technology Bureau of Sichuan provinceNational Natural Science Foundation of ChinaGraduate Education and Teaching Reform research project of Sichuan University3111-3122https://www.ebi.ac.uk/biostudies/studies/S-EPMC10643235biostudies-literatureUnknown39(11)<h4>Purpose</h4>The top citation article reflects the developmental milestone of a given field. The purpose of this bibliometric analysis was to identify and assess the 100 most-cited (T100) articles on the epigenetics mechanism of epilepsy.<h4>Methods</h4>The Web of Science Core Collection (WoSCC) database was used to investigate, and search terms related to epilepsy epigenetics were compiled. Results were ranked according to citation number. The publication year, citation density, authorship, journal, country, institution, manuscript type, theme, and clinical topics were further evaluated.<h4>Results</h4>The Web of Science search returned a total of 1231 manuscripts. The number of citations for a manuscript ranges from 739 to 75. The greatest number of manuscripts in the top 100 was publChild's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryThe 100 most-cited manuscripts in epilepsy epigenetics: a bibliometric analysis.PMC10643235GSSCU202115682071686KL115, KL0722021YFS0093Liu LFan LGan JRao XWang XLuo HfalseThe 100 most-cited manuscripts in epilepsy epigenetics: a bibliometric analysis.<h4>Purpose</h4>The top citation article reflects the developmental milestone of a given field. The purpose of this bibliometric analysis was to identify and assess the 100 most-cited (T100) articles on the epigenetics mechanism of epilepsy.<h4>Methods</h4>The Web of Science Core Collection (WoSCC) database was used to investigate, and search terms related to epilepsy epigenetics were compiled. Results were ranked according to citation number. The publication year, citation density, authorship, journal, country, institution, manuscript type, theme, and clinical topics were further evaluated.<h4>Results</h4>The Web of Science search returned a total of 1231 manuscripts. The number of citations for a manuscript ranges from 739 to 75. The greatest number of manuscripts in the top 100 was publ2023-01-01T00:00:00Z2023 Nov2026-06-01T08:12:43.347Z2025-04-04T19:15:43.719ZS-EPMC106432353734027310.1007/s00381-023-06032-w