{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Benedetti E"],"pubmed_abstract":["<h4>Introduction</h4>Neutropenic enterocolitis (NEC) is a life-threatening complication reported in patients with acute myeloid leukemia (AML) following chemotherapy (CHT). Intensive induction and consolidation CHT may damage intestinal mucosa leading to a NEC episode (NECe). NEC reported mortality may be up to 30-60%. Early US-guided bed-side diagnosis and prompt treatment may substantially improve the survival. An emerging worldwide concern is the intestinal colonization by multi-drug-resistant bacteria especially when patients are exposed to chemotherapy regimens potentially correlated to mucosal damage.<h4>Methods</h4>In our study we prospectively enrolled all AML patients admitted in our leukemia unit to receive intensive induction and consolidation chemotherapy and experiencing chemo"],"journal":["Frontiers in oncology"],"pagination":["1272072"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10646482"],"repository":["biostudies-literature"],"pubmed_title":["Impact of different chemotherapy regimens on intestinal mucosal injury assessed with bedside ultrasound: a study in 213 AML patients."],"pmcid":["PMC10646482"],"pubmed_authors":["Bruno B","Giubbolini R","Ricchiuto V","Arena C","Stella SM","Neri E","Bramanti E","Pucci G","Susini MC","Galimberti S","Mavilia F","Mazzantini E","Traverso G","Cerri F","Benedetti E","De Simone L","Lippolis P","Capochiani E","Valentini K","Morganti R"],"additional_accession":[]},"is_claimable":false,"name":"Impact of different chemotherapy regimens on intestinal mucosal injury assessed with bedside ultrasound: a study in 213 AML patients.","description":"<h4>Introduction</h4>Neutropenic enterocolitis (NEC) is a life-threatening complication reported in patients with acute myeloid leukemia (AML) following chemotherapy (CHT). Intensive induction and consolidation CHT may damage intestinal mucosa leading to a NEC episode (NECe). NEC reported mortality may be up to 30-60%. Early US-guided bed-side diagnosis and prompt treatment may substantially improve the survival. An emerging worldwide concern is the intestinal colonization by multi-drug-resistant bacteria especially when patients are exposed to chemotherapy regimens potentially correlated to mucosal damage.<h4>Methods</h4>In our study we prospectively enrolled all AML patients admitted in our leukemia unit to receive intensive induction and consolidation chemotherapy and experiencing chemo","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-26T21:15:39.77Z","creation":"2025-02-19T00:38:19.415Z"},"accession":"S-EPMC10646482","cross_references":{"pubmed":["38023169"],"doi":["10.3389/fonc.2023.1272072"]}}