biostudies-literatureUnknown13Benedetti E<h4>Introduction</h4>Neutropenic enterocolitis (NEC) is a life-threatening complication reported in patients with acute myeloid leukemia (AML) following chemotherapy (CHT). Intensive induction and consolidation CHT may damage intestinal mucosa leading to a NEC episode (NECe). NEC reported mortality may be up to 30-60%. Early US-guided bed-side diagnosis and prompt treatment may substantially improve the survival. An emerging worldwide concern is the intestinal colonization by multi-drug-resistant bacteria especially when patients are exposed to chemotherapy regimens potentially correlated to mucosal damage.<h4>Methods</h4>In our study we prospectively enrolled all AML patients admitted in our leukemia unit to receive intensive induction and consolidation chemotherapy and experiencing chemoFrontiers in oncology1272072https://www.ebi.ac.uk/biostudies/studies/S-EPMC10646482biostudies-literatureImpact of different chemotherapy regimens on intestinal mucosal injury assessed with bedside ultrasound: a study in 213 AML patients.PMC10646482Bruno BGiubbolini RRicchiuto VArena CStella SMNeri EBramanti EPucci GSusini MCGalimberti SMavilia FMazzantini ETraverso GCerri FBenedetti EDe Simone LLippolis PCapochiani EValentini KMorganti RfalseImpact of different chemotherapy regimens on intestinal mucosal injury assessed with bedside ultrasound: a study in 213 AML patients.<h4>Introduction</h4>Neutropenic enterocolitis (NEC) is a life-threatening complication reported in patients with acute myeloid leukemia (AML) following chemotherapy (CHT). Intensive induction and consolidation CHT may damage intestinal mucosa leading to a NEC episode (NECe). NEC reported mortality may be up to 30-60%. Early US-guided bed-side diagnosis and prompt treatment may substantially improve the survival. An emerging worldwide concern is the intestinal colonization by multi-drug-resistant bacteria especially when patients are exposed to chemotherapy regimens potentially correlated to mucosal damage.<h4>Methods</h4>In our study we prospectively enrolled all AML patients admitted in our leukemia unit to receive intensive induction and consolidation chemotherapy and experiencing chemo2023-01-01T00:00:00Z20232025-04-26T21:15:39.77Z2025-02-19T00:38:19.415ZS-EPMC106464823802316910.3389/fonc.2023.1272072