biostudies-literatureUnknown71(3)Nakamiya KBy using 1,4-dioxane as the sole source of carbon, a 1,4-dioxane-degrading microorganism was isolated from soil. The fungus, termed strain A, was able to utilize 1,4-dioxane and many kinds of cyclic ethers as the sole source of carbon and was identified as Cordyceps sinensis from its 18S rRNA gene sequence. Ethylene glycol was identified as a degradation product of 1,4-dioxane by the use of deuterated 1,4-dioxane-d8 and gas chromatography-mass spectrometry analysis. A degradation pathway involving ethylene glycol, glycolic acid, and oxalic acid was proposed, followed by incorporation of the glycolic acid and/or oxalic acid via glyoxylic acid into the tricarboxylic acid cycle.Applied and environmental microbiology1254-8https://www.ebi.ac.uk/biostudies/studies/S-EPMC1065185biostudies-literatureDegradation of 1,4-dioxane and cyclic ethers by an isolated fungus.PMC1065185Nakamiya KHashimoto SIto HMorita MEdmonds JSfalseDegradation of 1,4-dioxane and cyclic ethers by an isolated fungus.By using 1,4-dioxane as the sole source of carbon, a 1,4-dioxane-degrading microorganism was isolated from soil. The fungus, termed strain A, was able to utilize 1,4-dioxane and many kinds of cyclic ethers as the sole source of carbon and was identified as Cordyceps sinensis from its 18S rRNA gene sequence. Ethylene glycol was identified as a degradation product of 1,4-dioxane by the use of deuterated 1,4-dioxane-d8 and gas chromatography-mass spectrometry analysis. A degradation pathway involving ethylene glycol, glycolic acid, and oxalic acid was proposed, followed by incorporation of the glycolic acid and/or oxalic acid via glyoxylic acid into the tricarboxylic acid cycle.2005-01-01T00:00:00Z2005 Mar2024-11-06T01:04:38.634Z2019-03-27T01:08:44ZS-EPMC10651851574632610.1128/aem.71.3.1254-1258.200510.1128/AEM.71.3.1254-1258.2005