{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["339"],"submitter":["Ji C"],"pubmed_abstract":["Circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses are highly diverse and have a broad range of hosts. In this study, we report the detection of Bo-Circo-like virus AH20-1 in the feces of diarrheal cattle. The virus has a circular genome of 3,912 nucleotides, three major putative open reading frames, and encodes a Rep gene of 310 amino acids. We found that the virus is closely related to the Bo-Circo-like virus CH strain, which belongs to the novel Kirkoviridae family. Furthermore, we conducted a nationwide surveillance program and found that the virus is prevalent in China (23.6%, 205/868), with the BCLa subtype being the predominant strain. Our findings suggest that the virus can infect sheep, highlighting the potential for cross-species transmissi"],"journal":["Virus research"],"pagination":["199204"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10654594"],"repository":["biostudies-literature"],"pubmed_title":["Circular replication-associated protein-encoding single-stranded DNA virus with risk of spillover is widely prevalent in domestic animals in China."],"pmcid":["PMC10654594"],"pubmed_authors":["Gong F","Ji C","Pan Z","Zhang Y","Feng Y","Zhang X","Yao H","Sun X"],"additional_accession":[]},"is_claimable":false,"name":"Circular replication-associated protein-encoding single-stranded DNA virus with risk of spillover is widely prevalent in domestic animals in China.","description":"Circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses are highly diverse and have a broad range of hosts. In this study, we report the detection of Bo-Circo-like virus AH20-1 in the feces of diarrheal cattle. The virus has a circular genome of 3,912 nucleotides, three major putative open reading frames, and encodes a Rep gene of 310 amino acids. We found that the virus is closely related to the Bo-Circo-like virus CH strain, which belongs to the novel Kirkoviridae family. Furthermore, we conducted a nationwide surveillance program and found that the virus is prevalent in China (23.6%, 205/868), with the BCLa subtype being the predominant strain. Our findings suggest that the virus can infect sheep, highlighting the potential for cross-species transmissi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2025-04-03T22:18:18.602Z","creation":"2024-10-15T17:38:40.347Z"},"accession":"S-EPMC10654594","cross_references":{"pubmed":["37607596"],"doi":["10.1016/j.virusres.2023.199204"]}}