{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(11)"],"submitter":["Kabirian R"],"pubmed_abstract":["<h4>Importance</h4>Younger survivors of breast cancer frequently report more treatment-related symptoms, mostly related to the menopausal transition.<h4>Objective</h4>To assess factors associated with chemotherapy-related amenorrhea (CRA) and to evaluate its association with long-term quality of life (QOL).<h4>Design, setting, and participants</h4>The prospective, longitudinal Cancer Toxicities Study, a multicenter French cohort study, includes women with a diagnosis of stage I to III breast cancer and collects data approximately yearly after diagnosis. The current study reports outcomes up to 4 years after diagnosis for participants enrolled from 2012 to 2017. Participants included premenopausal women younger than 50 years treated with chemotherapy and not receiving adjuvant ovarian funct"],"journal":["JAMA network open"],"pagination":["e2343910"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10654794"],"repository":["biostudies-literature"],"pubmed_title":["Chemotherapy-Related Amenorrhea and Quality of Life Among Premenopausal Women With Breast Cancer."],"pmcid":["PMC10654794"],"pubmed_authors":["Dhaini Merimeche A","Kabirian R","Tredan O","Levy C","Havas J","Martin AL","Giacchetti S","Dalenc F","Everhard S","Pistilli B","Rouanet P","Vaz-Luis I","Franzoi MA","Guillermet S","Lambertini M","Ferrero JM","Di Meglio A","Cottu P","Coutant C","Petit T"],"additional_accession":[]},"is_claimable":false,"name":"Chemotherapy-Related Amenorrhea and Quality of Life Among Premenopausal Women With Breast Cancer.","description":"<h4>Importance</h4>Younger survivors of breast cancer frequently report more treatment-related symptoms, mostly related to the menopausal transition.<h4>Objective</h4>To assess factors associated with chemotherapy-related amenorrhea (CRA) and to evaluate its association with long-term quality of life (QOL).<h4>Design, setting, and participants</h4>The prospective, longitudinal Cancer Toxicities Study, a multicenter French cohort study, includes women with a diagnosis of stage I to III breast cancer and collects data approximately yearly after diagnosis. The current study reports outcomes up to 4 years after diagnosis for participants enrolled from 2012 to 2017. Participants included premenopausal women younger than 50 years treated with chemotherapy and not receiving adjuvant ovarian funct","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2026-06-02T01:17:24.314Z","creation":"2025-04-06T02:39:43.158Z"},"accession":"S-EPMC10654794","cross_references":{"pubmed":["37971739"],"doi":["10.1001/jamanetworkopen.2023.43910"]}}