{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xia H"],"funding":["Beijing Municipal Natural Science Foundation","Peking University Medicine Sailing Program for Young Scholars' Scientific & Technological Innovation"],"pagination":["467"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10655441"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>To explore the predictive value of Ellipsoid Zone (EZ) -related angle parameters for the outcome of primary macular hole surgery.<h4>Methods</h4>This was a retrospective study. Patients diagnosed with large macular hole (MH) (minimum diameter > 500 μm) between 2018 and 2021 were enrolled. All patients underwent 25-gauge pars plana vitrectomy, internal limiting membrane (ILM) peeling and air tamponade. Spectral-domain OCT (SD-OCT) and best corrected visual acuity (BCVA) were measured in preoperative and 2-week post-operative. Classic and angle related parameters were measured via ImageJ. Angle regularity (AR) were defined as the standard deviation of the angle parameters in vertical and horizontal direction.<h4>Results</h4>Seventy-six eyes were included for analysis; 24 e"],"journal":["BMC ophthalmology"],"pubmed_title":["Predictive value of ellipsoid zone-related angle parameters in primary surgery of large macular hole: a case control study."],"pmcid":["PMC10655441"],"funding_grant_id":["7202229","BMU2023YFJHPY031"],"pubmed_authors":["Dou H","Xia H","Liao Y","Li X","Yang J","Ding Y","Wang X","Shi Y"],"additional_accession":[]},"is_claimable":false,"name":"Predictive value of ellipsoid zone-related angle parameters in primary surgery of large macular hole: a case control study.","description":"<h4>Background</h4>To explore the predictive value of Ellipsoid Zone (EZ) -related angle parameters for the outcome of primary macular hole surgery.<h4>Methods</h4>This was a retrospective study. Patients diagnosed with large macular hole (MH) (minimum diameter > 500 μm) between 2018 and 2021 were enrolled. All patients underwent 25-gauge pars plana vitrectomy, internal limiting membrane (ILM) peeling and air tamponade. Spectral-domain OCT (SD-OCT) and best corrected visual acuity (BCVA) were measured in preoperative and 2-week post-operative. Classic and angle related parameters were measured via ImageJ. Angle regularity (AR) were defined as the standard deviation of the angle parameters in vertical and horizontal direction.<h4>Results</h4>Seventy-six eyes were included for analysis; 24 e","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2025-04-21T23:57:36.612Z","creation":"2025-04-05T19:20:21.872Z"},"accession":"S-EPMC10655441","cross_references":{"pubmed":["37978355"],"doi":["10.1186/s12886-023-03187-7"]}}