biostudies-literatureUnknown14Leoni FThe spread of extended-spectrum β-lactamase (ESBL)-producing <i>Escherichia coli</i> is a major public health issue. Bivalves are filter-feeder animals capable of bioaccumulating the microorganisms present in water. This physiological characteristic makes them both good indicators of environmental contamination and possible carriers of pathogenic bacteria, including those resistant to antimicrobials. The aim of this study was to investigate the occurrence of ESBL-producing <i>E. coli</i> in clams (<i>n</i> = 308) collected from harvesting areas of the Central Adriatic Sea between 2018 and 2019. ESBL- /class C β-lactamase (AmpC)- producing <i>E. coli</i> and <i>Escherichia</i> spp. were isolated by streaking over the surface of MacConkey agar plates supplemented with cefotaxime enriched broFrontiers in microbiology1219008https://www.ebi.ac.uk/biostudies/studies/S-EPMC10657901biostudies-literatureOccurrence and temporal distribution of extended-spectrum β-lactamase-producing <i>Escherichia coli</i> in clams from the Central Adriatic, Italy.PMC10657901Barchiesi FMassacci FRPieralisi SCucco LDuranti AAngelico GMagistrali CFAlbini ERinaldi ASecondini BLeoni FSacchini LCamma CfalseOccurrence and temporal distribution of extended-spectrum β-lactamase-producing <i>Escherichia coli</i> in clams from the Central Adriatic, Italy.The spread of extended-spectrum β-lactamase (ESBL)-producing <i>Escherichia coli</i> is a major public health issue. Bivalves are filter-feeder animals capable of bioaccumulating the microorganisms present in water. This physiological characteristic makes them both good indicators of environmental contamination and possible carriers of pathogenic bacteria, including those resistant to antimicrobials. The aim of this study was to investigate the occurrence of ESBL-producing <i>E. coli</i> in clams (<i>n</i> = 308) collected from harvesting areas of the Central Adriatic Sea between 2018 and 2019. ESBL- /class C β-lactamase (AmpC)- producing <i>E. coli</i> and <i>Escherichia</i> spp. were isolated by streaking over the surface of MacConkey agar plates supplemented with cefotaxime enriched bro2023-01-01T00:00:00Z20232026-04-08T13:09:30.273Z2025-02-19T01:51:59.352ZS-EPMC106579013802916610.3389/fmicb.2023.1219008