{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li F"],"funding":["the Clinical Research Project of Shenzhen Dapeng New District Medicine and Health Group","the Yu Miao Project of Shenzhen Dapeng New District Medicine and Health Group"],"pagination":["20361"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10663442"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Our study aimed to explore the association between serum C-reactive protein (CRP) and COVID-19 mortality. This is a retrospective cohort study of all patients admitted to 4 hospitals within the Montefiore Health System between March 1 and April 16, 2020, with SARS-CoV-2 infection. All-cause mortality were collected in 7 May 2020. The mortality risk was estimated using Cox proportional hazards models. Of the 3545 patients with a median age of 63.7 years, 918 (25.9%) died within the time of cohort data collection after admission. When the CRP was < 15.6 mg/L, the mortality rate increased with an adjusted HR of 1.57 (95% CI 1.30-1.91, P < 0.0001) for every 10 mg/L increment in the CRP. When the CRP was ≥ 15.6 mg/L, the mortality rate increased with an adjusted HR of 1.11 (95% CI 0.99-1.24, P "],"journal":["Scientific reports"],"pubmed_title":["Association of C-reactive protein with mortality in Covid-19 patients: a secondary analysis of a cohort study."],"pmcid":["PMC10663442"],"funding_grant_id":["No.2022JTLCYJ06","No.2021JTYM04"],"pubmed_authors":["Zhou M","Lai Y","Liu Z","Zhu Y","Li F","He M","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"Association of C-reactive protein with mortality in Covid-19 patients: a secondary analysis of a cohort study.","description":"Our study aimed to explore the association between serum C-reactive protein (CRP) and COVID-19 mortality. This is a retrospective cohort study of all patients admitted to 4 hospitals within the Montefiore Health System between March 1 and April 16, 2020, with SARS-CoV-2 infection. All-cause mortality were collected in 7 May 2020. The mortality risk was estimated using Cox proportional hazards models. Of the 3545 patients with a median age of 63.7 years, 918 (25.9%) died within the time of cohort data collection after admission. When the CRP was < 15.6 mg/L, the mortality rate increased with an adjusted HR of 1.57 (95% CI 1.30-1.91, P < 0.0001) for every 10 mg/L increment in the CRP. When the CRP was ≥ 15.6 mg/L, the mortality rate increased with an adjusted HR of 1.11 (95% CI 0.99-1.24, P ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2026-05-29T05:59:16.045Z","creation":"2024-11-19T23:43:59.904Z"},"accession":"S-EPMC10663442","cross_references":{"pubmed":["37990060"],"doi":["10.1038/s41598-023-47680-x"]}}