biostudies-literatureUnknown10Monti G<h4>Objective</h4>Sepsis and septic shock are major challenges and economic burdens to healthcare, impacting millions of people globally and representing significant causes of mortality. Recently, a large number of quality improvement programs focused on sepsis resuscitation bundles have been instituted worldwide. These educational initiatives have been shown to be associated with improvements in clinical outcomes. We aimed to evaluate the impact of a multi-faceted quality implementing program (QIP) on the compliance of a "simplified 1-h bundle" (Sepsis 6) and hospital mortality of severe sepsis and septic shock patients out of the intensive care unit (ICU).<h4>Methods</h4>Emergency departments (EDs) and medical wards (MWs) of 12 academic and non-academic hospitals in the Lombardy region (Frontiers in medicine1215341https://www.ebi.ac.uk/biostudies/studies/S-EPMC10680451biostudies-literatureEffect of a quality improvement program on compliance to the sepsis bundle in non-ICU patients: a multicenter prospective before and after cohort study.PMC10680451Nova AFerrante LTraficante RVarisco ELorini CBornaghi MGalotti PSciascera AMarchesi GMartini FSantambrogio TVesconi S“Lotta alla Sepsi” Team Study GroupTengattin FMonti GSerra GBeck ECarrara GFerrari NQuarteroni SBonalume WMinoja GNattino GErhan GMorra SPecorino MMarchesi STonolli BPadovani MMargarito FRanzini MSavioli MFumagalli RCanegrati VLattuada MMeo MOrtolan MManin LBosisio SFabbri CRadrizzani DCaironi PBonfanti PGallotta GRezoagli ECortellaro FSavojardo VCapra Marzani FZarienato MCalini ATaje MAlborghetti MTira TDe Lucia MSpitoni MGAceti MCecchin AFranchini SQuaini ABrusa ECapra RGavazzi PVilla PGreco STresoldi MGrassi DZeroli CCiccone SfalseEffect of a quality improvement program on compliance to the sepsis bundle in non-ICU patients: a multicenter prospective before and after cohort study.<h4>Objective</h4>Sepsis and septic shock are major challenges and economic burdens to healthcare, impacting millions of people globally and representing significant causes of mortality. Recently, a large number of quality improvement programs focused on sepsis resuscitation bundles have been instituted worldwide. These educational initiatives have been shown to be associated with improvements in clinical outcomes. We aimed to evaluate the impact of a multi-faceted quality implementing program (QIP) on the compliance of a "simplified 1-h bundle" (Sepsis 6) and hospital mortality of severe sepsis and septic shock patients out of the intensive care unit (ICU).<h4>Methods</h4>Emergency departments (EDs) and medical wards (MWs) of 12 academic and non-academic hospitals in the Lombardy region (2023-01-01T00:00:00Z20232025-04-05T10:23:27.539Z2025-02-18T23:30:34.02ZS-EPMC106804513802012810.3389/fmed.2023.1215341