{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang L"],"funding":["Key Research and Development Projects of Shanxi Province","Basic Research Project of Shanxi Province"],"pagination":["3000605231199019"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10683577"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["51(9)"],"pubmed_abstract":["Pulmonary nodules are usually considered to be associated with malignant tumors and benign lesions, such as granuloma, pulmonary lymph nodes, fibrosis, and inflammatory lesions. Clinical cases of pulmonary nodules associated with hemophagocytic lymphohistiocytosis have rarely been reported. Therefore, when patients develop pulmonary nodules, the possibility of developing hemophagocytic lymphohistiocytosis is often not considered. We report the first case of familial hemophagocytic lymphohistiocytosis with recurrent pulmonary nodules as the first symptom. Our findings will hopefully provide new ideas for the diagnosis and treatment of pulmonary nodules in the future."],"journal":["The Journal of international medical research"],"pubmed_title":["Repeated pulmonary nodules as the primary symptom of familial hemophagocytic lymphohistiocytosis in adults: a case report and review."],"pmcid":["PMC10683577"],"funding_grant_id":["201903D421066","202203021211029"],"pubmed_authors":["Cheng E","Dong Y","Liu L","Wu Q","Xing Y","Zhang L","Li X","Li Y","Feng L","Xinrui T","Ge X","Huo R","Dong C"],"additional_accession":[]},"is_claimable":false,"name":"Repeated pulmonary nodules as the primary symptom of familial hemophagocytic lymphohistiocytosis in adults: a case report and review.","description":"Pulmonary nodules are usually considered to be associated with malignant tumors and benign lesions, such as granuloma, pulmonary lymph nodes, fibrosis, and inflammatory lesions. Clinical cases of pulmonary nodules associated with hemophagocytic lymphohistiocytosis have rarely been reported. Therefore, when patients develop pulmonary nodules, the possibility of developing hemophagocytic lymphohistiocytosis is often not considered. We report the first case of familial hemophagocytic lymphohistiocytosis with recurrent pulmonary nodules as the first symptom. Our findings will hopefully provide new ideas for the diagnosis and treatment of pulmonary nodules in the future.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2026-07-14T16:48:50.769Z","creation":"2025-04-06T22:45:45.616Z"},"accession":"S-EPMC10683577","cross_references":{"pubmed":["37756585"],"doi":["10.1177/03000605231199019"]}}