{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(11)"],"submitter":["Gruber M"],"pubmed_abstract":["<h4>Background</h4>Atrial fibrillation (AF) increases heart failure (HF) risk. Whereas the risk of HF-related hospitalization and mortality are known in the setting of AF, the impact of AF treatment on HF development is understudied.<h4>Objective</h4>The purpose of this study was to compare HF incidence among AF patients treated with antiarrhythmic drugs (AADs) vs catheter ablation (CA).<h4>Methods</h4>AF patients with 1 prior AAD usage were identified in 2014-2022 Optum Clinformatics database. Patients were classified into 2 cohorts: those receiving CA vs those receiving a different AAD prescription. The 2 cohorts were matched on sociodemographic and clinical covariates using propensity score matching technique. Cox regression model was used to compare incident HF risk in the 2 cohorts. S"],"journal":["Heart rhythm O2"],"pagination":["681-691"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10685151"],"repository":["biostudies-literature"],"pubmed_title":["Heart failure risk in patients with atrial fibrillation treated with catheter ablation vs antiarrhythmic drugs."],"pmcid":["PMC10685151"],"pubmed_authors":["Karim S","Zhang D","Gruber M","Khanna R","Iglesias M"],"additional_accession":[]},"is_claimable":false,"name":"Heart failure risk in patients with atrial fibrillation treated with catheter ablation vs antiarrhythmic drugs.","description":"<h4>Background</h4>Atrial fibrillation (AF) increases heart failure (HF) risk. Whereas the risk of HF-related hospitalization and mortality are known in the setting of AF, the impact of AF treatment on HF development is understudied.<h4>Objective</h4>The purpose of this study was to compare HF incidence among AF patients treated with antiarrhythmic drugs (AADs) vs catheter ablation (CA).<h4>Methods</h4>AF patients with 1 prior AAD usage were identified in 2014-2022 Optum Clinformatics database. Patients were classified into 2 cohorts: those receiving CA vs those receiving a different AAD prescription. The 2 cohorts were matched on sociodemographic and clinical covariates using propensity score matching technique. Cox regression model was used to compare incident HF risk in the 2 cohorts. S","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2025-04-26T00:17:37.663Z","creation":"2025-04-06T09:41:09.463Z"},"accession":"S-EPMC10685151","cross_references":{"pubmed":["38034885"],"doi":["10.1016/j.hroo.2023.09.009"]}}