biostudies-literatureZbytniewska-Megret MNational Research Foundation, Prime Minister’s Office, Singapore under its Campus for Research Excellence and Technological Enterprise programmeSwiss National Science FoundationDeutsche Forschungsgemeinschaft823-836https://www.ebi.ac.uk/biostudies/studies/S-EPMC10685702biostudies-literatureUnknown37(11-12)<h4>Background</h4>Hand proprioception is essential for fine movements and therefore many activities of daily living. Although frequently impaired after stroke, it is unclear how hand proprioception evolves in the sub-acute phase and whether it follows a similar pattern of changes as motor impairments.<h4>Objective</h4>This work investigates whether there is a corresponding pattern of changes over time in hand proprioception and motor function as comprehensively quantified by a combination of robotic, clinical, and neurophysiological assessments.<h4>Methods</h4>Finger proprioception (position sense) and motor function (force, velocity, range of motion) were evaluated using robotic assessments at baseline (<3 months after stroke) and up to 4 weeks later (discharge). Clinical assessments (amNeurorehabilitation and neural repairThe Evolution of Hand Proprioceptive and Motor Impairments in the Sub-Acute Phase After Stroke.PMC10685702320030L_170163170163Lambercy OGassert RKanzler CMZbytniewska-Megret MSalzmann CLiepert JHassa TfalseThe Evolution of Hand Proprioceptive and Motor Impairments in the Sub-Acute Phase After Stroke.<h4>Background</h4>Hand proprioception is essential for fine movements and therefore many activities of daily living. Although frequently impaired after stroke, it is unclear how hand proprioception evolves in the sub-acute phase and whether it follows a similar pattern of changes as motor impairments.<h4>Objective</h4>This work investigates whether there is a corresponding pattern of changes over time in hand proprioception and motor function as comprehensively quantified by a combination of robotic, clinical, and neurophysiological assessments.<h4>Methods</h4>Finger proprioception (position sense) and motor function (force, velocity, range of motion) were evaluated using robotic assessments at baseline (<3 months after stroke) and up to 4 weeks later (discharge). Clinical assessments (am2023-01-01T00:00:00Z2023 Dec2025-04-22T08:09:00.361Z2025-02-19T04:43:57.543ZS-EPMC106857023795359510.1177/15459683231207355