{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(12)"],"submitter":["Knoshaug EP"],"pubmed_abstract":["The rapid accumulation of sequenced plant genomes in the past decade has outpaced the still difficult problem of genome-wide protein-coding gene annotation. A substantial fraction of protein-coding genes in all plant genomes are poorly annotated or unannotated and remain functionally uncharacterized. We identified unannotated proteins in three model organisms representing distinct branches of the green lineage (Viridiplantae): <i>Arabidopsis thaliana</i> (eudicot), <i>Setaria viridis</i> (monocot), and <i>Chlamydomonas reinhardtii</i> (Chlorophyte alga). Using similarity searching, we identified a subset of unannotated proteins that were conserved between these species and defined them as Deep Green proteins. Bioinformatic, genomic, and structural predictions were performed to begin classi"],"journal":["Plant direct"],"pagination":["e527"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10690477"],"repository":["biostudies-literature"],"pubmed_title":["Identification and preliminary characterization of conserved uncharacterized proteins from <i>Chlamydomonas reinhardtii</i>, <i>Arabidopsis thaliana</i>, and <i>Setaria viridis</i>."],"pmcid":["PMC10690477"],"pubmed_authors":["Umen J","Liu J","Nguyen H","Sun P","Mattoon EM","Knoshaug EP","Zhang N","St John P","Chen C","Nag A","Zhang R","Cheng J"],"additional_accession":[]},"is_claimable":false,"name":"Identification and preliminary characterization of conserved uncharacterized proteins from <i>Chlamydomonas reinhardtii</i>, <i>Arabidopsis thaliana</i>, and <i>Setaria viridis</i>.","description":"The rapid accumulation of sequenced plant genomes in the past decade has outpaced the still difficult problem of genome-wide protein-coding gene annotation. A substantial fraction of protein-coding genes in all plant genomes are poorly annotated or unannotated and remain functionally uncharacterized. We identified unannotated proteins in three model organisms representing distinct branches of the green lineage (Viridiplantae): <i>Arabidopsis thaliana</i> (eudicot), <i>Setaria viridis</i> (monocot), and <i>Chlamydomonas reinhardtii</i> (Chlorophyte alga). Using similarity searching, we identified a subset of unannotated proteins that were conserved between these species and defined them as Deep Green proteins. Bioinformatic, genomic, and structural predictions were performed to begin classi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2025-05-31T23:32:32.894Z","creation":"2024-11-12T08:30:02.688Z"},"accession":"S-EPMC10690477","cross_references":{"pubmed":["38044962"],"doi":["10.1002/pld3.527"]}}