biostudies-literatureUnknown6(12)Ma TM<h4>Importance</h4>Novel hormonal therapy (NHT) agents have been shown to prolong overall survival in numerous randomized clinical trials for patients with advanced prostate cancer (PCa). There is a paucity of data regarding the pattern of use of these agents in patients from different racial and ethnic groups.<h4>Objective</h4>To assess racial and ethnic disparities in the use of NHT in patients with advanced PCa.<h4>Design, setting, and participants</h4>This cohort study comprised all men diagnosed with de novo advanced PCa (distant metastatic [M1], regional [N1M0], and high-risk localized [N0M0] per Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy [STAMPEDE] trial criteria) with Medicare Part A, B, and D coverage between January 1, 2011, and DecemJAMA network opene2345906https://www.ebi.ac.uk/biostudies/studies/S-EPMC10692845biostudies-literatureRacial and Ethnic Disparities in Use of Novel Hormonal Therapy Agents in Patients With Prostate Cancer.PMC10692845Agarwal NSpratt DKishan AUVapiwala NGarraway ISteinberg MLRettig MBMa TMMahal BValle LFXiang MBarragan-Carrillo RfalseRacial and Ethnic Disparities in Use of Novel Hormonal Therapy Agents in Patients With Prostate Cancer.<h4>Importance</h4>Novel hormonal therapy (NHT) agents have been shown to prolong overall survival in numerous randomized clinical trials for patients with advanced prostate cancer (PCa). There is a paucity of data regarding the pattern of use of these agents in patients from different racial and ethnic groups.<h4>Objective</h4>To assess racial and ethnic disparities in the use of NHT in patients with advanced PCa.<h4>Design, setting, and participants</h4>This cohort study comprised all men diagnosed with de novo advanced PCa (distant metastatic [M1], regional [N1M0], and high-risk localized [N0M0] per Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy [STAMPEDE] trial criteria) with Medicare Part A, B, and D coverage between January 1, 2011, and Decem2023-01-01T00:00:00Z2023 Dec2025-04-21T23:12:47.848Z2025-04-05T19:01:35.958ZS-EPMC106928453803900210.1001/jamanetworkopen.2023.45906