{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(6)"],"submitter":["Delmore KE"],"pubmed_abstract":["Structural variants (SVs) are a major source of genetic variation; and descriptions in natural populations and connections with phenotypic traits are beginning to accumulate in the literature. We integrated advances in genomic sequencing and animal tracking to begin filling this knowledge gap in the Eurasian blackcap. Specifically, we (a) characterized the genome-wide distribution, frequency, and overall fitness effects of SVs using haplotype-resolved assemblies for 79 birds, and (b) used these SVs to study the genetics of seasonal migration. We detected >15 K SVs. Many SVs overlapped repetitive regions and exhibited evidence of purifying selection suggesting they have overall deleterious effects on fitness. We used estimates of genomic differentiation to identify SVs exhibiting evidence o"],"journal":["Evolution letters"],"pagination":["401-412"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10693001"],"repository":["biostudies-literature"],"pubmed_title":["Structural genomic variation and migratory behavior in a wild songbird."],"pmcid":["PMC10693001"],"pubmed_authors":["Curk T","van der Jeugd HP","Van Doren BM","Ullrich K","Liedvogel M","Delmore KE"],"additional_accession":[]},"is_claimable":false,"name":"Structural genomic variation and migratory behavior in a wild songbird.","description":"Structural variants (SVs) are a major source of genetic variation; and descriptions in natural populations and connections with phenotypic traits are beginning to accumulate in the literature. We integrated advances in genomic sequencing and animal tracking to begin filling this knowledge gap in the Eurasian blackcap. Specifically, we (a) characterized the genome-wide distribution, frequency, and overall fitness effects of SVs using haplotype-resolved assemblies for 79 birds, and (b) used these SVs to study the genetics of seasonal migration. We detected >15 K SVs. Many SVs overlapped repetitive regions and exhibited evidence of purifying selection suggesting they have overall deleterious effects on fitness. We used estimates of genomic differentiation to identify SVs exhibiting evidence o","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2025-04-04T09:39:19.465Z","creation":"2025-04-04T09:39:19.465Z"},"accession":"S-EPMC10693001","cross_references":{"pubmed":["38045725"],"doi":["10.1093/evlett/qrad040"]}}