biostudies-literatureUnknown9(49)Wang SIntrinsic gain is a vital figure of merit in transistors, closely related to signal amplification, operation voltage, power consumption, and circuit simplification. However, organic thin-film transistors (OTFTs) targeted at high gain have suffered from challenges such as narrow subthreshold operating voltage, low-quality interface, and uncontrollable barrier. Here, we report a van der Waals metal-barrier interlayer-semiconductor junction-based OTFT, which shows ultrahigh performance including ultrahigh gain of ~10⁴, low saturation voltage, negligible hysteresis, and good stability. The high-quality van der Waals-contacted junctions are mainly attributed to patterning EGaIn liquid metal electrodes by low-energy microfluidic processes. The wide-bandgap semiconductor Ga₂Science advanceseadj4656https://www.ebi.ac.uk/biostudies/studies/S-EPMC10699771biostudies-literatureUltrahigh-gain organic transistors based on van der Waals metal-barrier interlayer-semiconductor junction.PMC10699771Han LLi ZQGuo XHu WSun YLi LZou YGao PHe ZHHuang YWang SZhao QZheng LLiu BChen XWang ZHu YXfalseUltrahigh-gain organic transistors based on van der Waals metal-barrier interlayer-semiconductor junction.Intrinsic gain is a vital figure of merit in transistors, closely related to signal amplification, operation voltage, power consumption, and circuit simplification. However, organic thin-film transistors (OTFTs) targeted at high gain have suffered from challenges such as narrow subthreshold operating voltage, low-quality interface, and uncontrollable barrier. Here, we report a van der Waals metal-barrier interlayer-semiconductor junction-based OTFT, which shows ultrahigh performance including ultrahigh gain of ~10⁴, low saturation voltage, negligible hysteresis, and good stability. The high-quality van der Waals-contacted junctions are mainly attributed to patterning EGaIn liquid metal electrodes by low-energy microfluidic processes. The wide-bandgap semiconductor Ga₂2023-01-01T00:00:00Z2023 Dec2025-04-04T08:32:02.752Z2025-04-04T08:32:02.752ZS-EPMC106997713805581010.1126/sciadv.adj4656