{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Schuller M"],"pubmed_abstract":["Benzimidazole opioids, often referred to as nitazenes, represent a subgroup of new psychoactive substances with a recent increase in fatal overdoses in the US and Europe. With a variety of analogs emerging on the illicit drug market, forensic labs are challenged to identify these potent drugs. We here present a simple quantitative approach for the determination of nine nitazene analogs, namely, clonitazene, etodesnitazene, etonitazene, etonitazepyne, flunitazene, isotonitazene, metodesnitazene, metonitazene, and protonitazene in whole blood using liquid-phase microextraction and electromembrane extraction in a 96-well format and liquid chromatography tandem mass spectrometry. Green and efficient sample preparation was accomplished by liquid-phase microextraction in a 96-well format and res"],"journal":["Journal of analytical toxicology"],"pagination":["bkad071"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10714918"],"repository":["biostudies-literature"],"pubmed_title":["High-throughput quantification of emerging ''nitazene'' benzimidazole opioid analogs by microextraction and UHPLC-MS/MS."],"pmcid":["PMC10714918"],"pubmed_authors":["Schuller M","Leere Oiestad AM","Pedersen-Bjergaard S","Lucic I","Oiestad EL"],"additional_accession":[]},"is_claimable":false,"name":"High-throughput quantification of emerging ''nitazene'' benzimidazole opioid analogs by microextraction and UHPLC-MS/MS.","description":"Benzimidazole opioids, often referred to as nitazenes, represent a subgroup of new psychoactive substances with a recent increase in fatal overdoses in the US and Europe. With a variety of analogs emerging on the illicit drug market, forensic labs are challenged to identify these potent drugs. We here present a simple quantitative approach for the determination of nine nitazene analogs, namely, clonitazene, etodesnitazene, etonitazene, etonitazepyne, flunitazene, isotonitazene, metodesnitazene, metonitazene, and protonitazene in whole blood using liquid-phase microextraction and electromembrane extraction in a 96-well format and liquid chromatography tandem mass spectrometry. Green and efficient sample preparation was accomplished by liquid-phase microextraction in a 96-well format and res","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Sep","modification":"2025-04-04T14:31:44.952Z","creation":"2025-04-04T14:31:44.952Z"},"accession":"S-EPMC10714918","cross_references":{"pubmed":["37700512"],"doi":["10.1093/jat/bkad071"]}}